耐力训练的影响区域在大脑中血清素代谢从火车上卸下的早期阶段期间的雌性老鼠。

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pswlak Langfort J, Baranczuk E、D, Chalimoniuk M, Lukacova N,马沙拉白葡萄酒J, Gorski J

耐力训练的影响区域在大脑中血清素代谢从火车上卸下的早期阶段期间的雌性老鼠。

细胞摩尔一般。2006 Oct-Nov; 26 (7 - 8): 1327 - 42。Epub 2006 8月1。

PubMed ID

16897368 (在PubMed

]

文摘

1。检查的效果是一个一轮nonexhaustive耐力运动对色氨酸(尝试)、5 -羟色胺(5 -),5-hydroxyindolacetic酸(5-HIAA)和色氨酸羟化酶(TpH energy)水平在老鼠大脑的不同部分(大脑皮层、小脑、下丘脑、中脑纹状体,髓质)耐力训练的最后一天,48 h后(从火车上卸下期间)。2。雌性老鼠受到六周耐力训练计划。培训的有效性评估通过测量无氧阈值(在)。高效液相色谱法(HPLC)是用来确定区域,5,和5-HIAA内容在大脑中,由气液色谱法和薄层色谱法用于确定血液中游离脂肪酸的水平。区域TpH energy水平衡量免疫印迹分析。3所示。两组大鼠接受耐力训练,在所有的大脑区域研究但小脑,5 -内容后显著降低最后一轮nonexhaustive耐力运动比在控制老鼠休息没有受到培训。同样,大脑皮层和纹状体,但不是小脑,5 /尝试比率显著降低在训练老鼠最后的最后训练最后一个48小时后一轮nonexhaustive锻炼管理下火车比控制时期。 TpH protein level was decreased by 15-25% after the last bout of exercise either during the training process or after the and 1 h bout of endurance exercise performed 48 h after cessation of endurance training in brain cortex and striatum but not cerebellar.4. These results indicate that the reduction in 5-HT level was the adaptive response to endurance training. The lowered 5-HT/Try ratio and lowered TpH protein level attained after the training process suggests and that this change may be, at least partially, attributed to downregulation of TpH activity.

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药物酶

药物	酶	类	生物	药理作用	行动
色氨酸	色氨酸5-hydroxylase 1	蛋白质	人类	未知的	底物	细节