Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.
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Citation
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MacLeod AM, Street LJ, Reeve AJ, Jelley RA, Sternfeld F, Beer MS, Stanton JA, Watt AP, Rathbone D, Matassa VG
Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.
J Med Chem. 1997 Oct 24;40(22):3501-3.
- PubMed ID
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9357515 [View in PubMed]
- Abstract
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Not Available
DrugBank Data that Cites this Article
- Binding Properties
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Drug Target Property Measurement pH Temperature (°C) 苏matriptan 5-hydroxytryptamine receptor 1B IC 50 (nM) 16 N/A N/A Details 苏matriptan 5-hydroxytryptamine receptor 1B IC 50 (nM) 27 N/A N/A Details 苏matriptan 5-hydroxytryptamine receptor 1D EC 50 (nM) 16 N/A N/A Details 苏matriptan 5-hydroxytryptamine receptor 1D IC 50 (nM) 5 N/A N/A Details 苏matriptan 5-hydroxytryptamine receptor 1D IC 50 (nM) 2400 N/A N/A Details 苏matriptan 5-hydroxytryptamine receptor 1F IC 50 (nM) >1000 N/A N/A Details