发展一个简化仪器的诊断和分级静坐不能在一群病人接受普鲁氯嗪。
文章的细节
-
引用
复制到剪贴板 -
文森博士
发展一个简化仪器的诊断和分级静坐不能在一群病人接受普鲁氯嗪。
J紧急情况。2006年8月,31 (2):139 - 45。
- PubMed ID
-
17044574 (在PubMed]
- 文摘
-
静坐不能的多巴胺D2受体拮抗剂是一种常见的副作用通常仍未确诊的。传统的诊断和分级工具繁琐,很难记住和使用。促进急诊科(ED)的评估急性药物引起的静坐不能,我试图获取和评估一个简化仪器使用数据库编译从三个急性药物引起的静坐不能的先前的研究。这些研究使用了传统仪器的前瞻性评估360 17 - 65岁成人ED患者接受静脉普鲁氯嗪(10毫克)治疗头痛、恶心和呕吐。简短的仪器是来源于长仪器使用Wilcoxon z检验识别个人发现大多数与静坐不能的诊断密切相关。然后我回顾应用短仪器成对使用的队列和仪器分析比较结果。敏感性,特异性和接受者操作特征曲线用于分析仪器上形成的诊断准确性的影响。在118年漫长的标准诊断静坐不能(32.8%;95%可信区间(CI) 28.0% -37.9%)患者诊断和短期静坐不能在120年(33.3%;95%可信区间28.5% - -38.5%)。 When akathisia was characterized categorically as either absent or present, the Short criteria agreed with the Long in 358 cases (99.4%; 95% CI 98.0%-99.9%). Treating the diagnoses established by the Long criteria as the gold standard, the Short instrument had a sensitivity of 100.0% (95% CI 96.9%-100%) and a specificity of 99.2% (95% CI 97.0%-99.9%). Regarding the accuracy of categorizing akathisia into four severity grades, the Short scale agreed in 325 of 360 cases (90.3%; 95% CI 86.7%-93.1%) and misgraded 35 cases (9.7%; 95% CI 6.9%-13.3%), 34 of which fell within one grade of the Long scale. The Short instrument is highly accurate in diagnosing acute drug-induced akathisia, in comparison with the Long criteria, in the ED setting. The Short instrument also provides fairly accurate grading of akathisia severity. This simplified instrument should facilitate the detection and treatment of akathisia in the ED.