Tafluprost:前列腺素模拟治疗青光眼。

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Pantcheva MB, Seibold路、Awadallah NS Kahook我

Tafluprost:前列腺素模拟治疗青光眼。

难以其他。2011年9月,28(9):707 - 15所示。doi: 10.1007 / s12325 - 011 - 0055 - 8。Epub 2011年8月18日。

PubMed ID

21858491 (在PubMed

]

文摘

目的:本文的目的是评估tafluprost的安全性和有效性,降低眼压的fluoroprostaglandin受体模拟,在开角青光眼和眼高血压。出版文献进行的方法:一个搜索PubMed数据库使用搜索词“tafluprost。”The literature search identified 48 publications, including clinical and preclinical studies, from 2003 to 2011. From these ressults, articles available in the English language and in full text were selected and systematically reviewed by the authors. RESULTS: Recent studies have shown that tafluprost is an effective IOP-lowering medication. Evidence based medicine also reveals that tafluprost is safe and well-tolerated. Preservative-free tafluprost is as potent as the preserved formulation, but with fewer and milder ocular surface side effects. CONCLUSION: Since its introduction in 2008, initial studies have demonstrated that preserved and preservative-free tafluprost formulations have proven efficacy and safety in the treatment of glaucoma and ocular hypertension. Larger studies with longer follow-up are needed to assess long-term safety, efficacy, and tolerability compared with other prostaglandin analogs used for treating glaucoma.

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药物

Tafluprost

药物靶点

药物	目标	类	生物	药理作用	行动
Tafluprost	前列腺素F2-alpha受体	蛋白质	人类	是的	受体激动剂	细节