治疗的安全性和有效性spinosad咀嚼片的跳蚤出没的猫。

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Paarlberg TE,怀斯曼年代,鳟鱼厘米,凯EA,斯奈德

治疗的安全性和有效性spinosad咀嚼片的跳蚤出没的猫。

J是兽医协会。2013年4月15日,242 (8):1092 - 8。doi: 10.2460 / javma.242.8.1092。

PubMed ID

23547672 (在PubMed

]

文摘

目的:比较安全性和有效性spinosad selamectin和确定这些产品对跳蚤过敏皮炎的影响(时尚)猫。设计:随机临床试验。动物- 211 client-owned猫。程序:猫> / = 5跳蚤评估兽医诊所被分配接受spinosad(8点50到100毫克/公斤(22.7至45.5毫克/磅),订单;n = 139)或selamectin(> / = 6毫克/公斤(> / = 2.7毫克/磅),局部;72)每月一次。跳蚤梳子计数和时尚分数决定第一天,天27至33岁,85年和95年之间,天(分别为评价1、2和3);第0天药物管理局的第一天。结果:最常见的副反应是呕吐(14.3%和2.4%的spinosad selamectin-treated猫,分别)。评价2和3几何平均数跳蚤计数为spinosad-treated猫明显低于selamectin-treated猫。 Percentage reductions in flea counts for the spinosad and selamectin groups were 97.5% and 88.8% (evaluation 2) and 99.3% and 97.7% (evaluation 3), respectively. At evaluations 2 and 3, 70.6% and 92.6% of spinosad-treated cats and 29.4% and 64.7% of selamectin-treated cats were free of fleas, respectively. Weighted FAD scores for spinosad- and selamectin-treated cats decreased 94.2% and 80.0% during the study, respectively. Spinosad tablets were successfully administered during 98.1% of treatments. CONCLUSIONS AND CLINICAL RELEVANCE: Results of this study indicated spinosad and selamectin both reduced flea counts and FAD scores for cats, although spinosad was more effective. Monthly oral administration of spinosad may be practical for treatment of flea infestations and FAD in cats.

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药物

Spinosad