在小猪azaperone-detomidine-butorphanol-ketamine和azaperone-tiletamine-zolazepam麻醉进行比较。

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Heinonen ML, Raekallio先生,Oliviero C, Ahokas年代,Peltoniemi OA

在小猪azaperone-detomidine-butorphanol-ketamine和azaperone-tiletamine-zolazepam麻醉进行比较。

兽医Anaesth。2009; 3月36 (2):151 - 7。doi: 10.1111 / j.1467-2995.2008.00443.x。

PubMed ID

19239653 (在PubMed

]

文摘

摘要目的:探讨阿扎哌隆、detomidine,布托啡诺和氯胺酮(它们的)猪和比较它与阿扎哌隆、tiletamine和zolazepam (TZ)。研究设计:前瞻性、随机、盲法、交叉研究。动物:12个临床健康猪杂交第16 - 25岁2个月,体重公斤。beplayapp方法:猪是pre-medicated阿扎哌隆(4毫克公斤(1))。十分钟后麻醉诱导与肌内它们(detomidine 0.08毫克公斤(1),布托啡诺0.2毫克公斤(1),氯胺酮10毫克公斤(1))或TZ (tiletamine和zolazepam 5毫克公斤(1))。猪被定位在背侧躺着。心跳和呼吸频率,姿势,麻醉得分,PaO(2),帕科(2),pH值和碳酸氢盐浓度测定。学习任务是用来比较time-anaesthesia指数曲线下的面积(AUC (anindex))之间的治疗。数据有关心脏和呼吸率,PaO(2),帕科(2)和麻醉评分分析重复测量的方差分析。魏克森讯号等级测试是用于数据关于镇静期间和麻醉。 RESULTS: The sedation, analgesia and anaesthesia lasted longer after DBK than TZ. The AUC(anscore) were 863 +/- 423 and 452 +/- 274 for DBK and TZ, respectively (p = 0.002). The duration of surgical anaesthesia lasted a median of 35 minutes (0-105 minutes) after DBK and a median of 15 minutes (0-35 minutes) after TZ (p = 0.05). Four pigs after DBK and six after TZ did not achieve the plane of surgical anaesthesia. The heart rate was lower after DBK than after TZ. Both treatments had similar effects on the other parameters measured. CONCLUSIONS: At the doses used DBK was more effective than TZ for anaesthesia in pigs under field conditions. CLINICAL RELEVANCE: The combinations can be used for sedation and minor field surgery in pigs. The doses and drugs chosen were insufficient to produce a reliable surgical plane of anaesthesia in these young pigs.

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药物

阿扎哌隆