使用包含的母牛cephalonium治疗和内部奶头密封剂,单独和组合。
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布拉德利AJ,布林我,佩恩B,威廉姆斯P,绿色的乔丹
使用包含的母牛cephalonium治疗和内部奶头密封剂,单独和组合。
J乳品科学。2010年4月,93 (4):1566 - 77。doi: 10.3168 / jds.2009 - 2725。
- PubMed ID
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20338434 (在PubMed]
- 文摘
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干燥时间是一个关键的泌乳周期,存在最优时间治愈现有乳房内的感染(IMI)以及包括新感染的敏感性最高的时期。目前,IMI在干旱时期控制抗生素的母牛疗法。本随机对照试验的目的是研究不同母牛治疗方案通过分层牛可能感染状况在较低的干燥在牛群体细胞计数(鳞状细胞癌;散装牛奶SCC < 250000细胞/毫升)英格兰西南部。四面八方的890头奶牛被招募。招募了奶牛被归类为感染或感染在鳞状细胞癌的基础和临床乳腺炎的历史。身体的同侧的季度在每个牛被随机分配接受1 4不同治疗方案类别根据其感染。季度high-SCC感染牛被分配接受抗生素的母牛疗法单独或结合一个内部奶头密封胶;季度low-SCC未受感染的牛都分配给接收奶头密封剂单独或结合抗生素的母牛疗法。所有季度采样细菌学的干燥,再在10 d post-calving。 Quarters were subsequently monitored for clinical mastitis for the first 100 d of lactation. The mass of residual sealant was assessed immediately post-calving to allow assessment of the association of sealant retention with treatment efficacy. Models were constructed to assess the efficacy of the different regimens in preventing IMI. Apparent cure rates of existing IMI with major pathogens were consistently >90% in quarters receiving antibiotic. Combination treatment of high-SCC infected cows resulted in an increased likelihood of being pathogen free post-calving (odds ratio=1.40; 95% credibility interval=1.03-1.90). The benefits of combination treatment of low-SCC uninfected cows were less clear. With respect to clinical mastitis, combination treatment of high-SCC infected cows resulted in a decreased likelihood of developing clinical mastitis in the first 100 d of the subsequent lactation (odds ratio=0.68; 95% credibility interval=0.48-0.98). The retention of the internal sealant was adversely affected by its use in combination with antibiotic dry cow therapy.
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