NAV

Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)is an influenza antigen used in seasonal influenza vaccines.

Generic Name
Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)
DrugBank Accession Number
DB14407
Background

seasonally-specific组件的流感vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Inactivated
Synonyms
Not Available

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Conditions
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
Improve clinical decision support with information oncontraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image
FLUQUADRI Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)(15 mcg/0.5ml)+Influenza A virus A/Brisbane/02/2018 (H1N1) recombinant hemagglutinin antigen(15 mcg/0.5ml)+甲型流感病毒A / South Australia/34/2019 IVR-197 (H3N2) antigen (formaldehyde inactivated)(15 mcg/0.5ml)+Influenza B virus B/Washington/02/2019 recombinant hemagglutinin antigen(15 mcg/0.5ml) Injection, suspension Intramuscular บริษัท ซาโนฟี่ ปาสเตอร์ จำกัด 2018-02-27 Not applicable Thailand flag
VAXİGRİP TETRA 0,5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR , 1 ADET Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)(15 mcg)+Influenza A virus A/Michigan/45/2015 X-275 (H1N1) hemagglutinin antigen (formaldehyde inactivated)(15 mcg)+甲型流感病毒A / Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (UV, formaldehyde inactivated)(15 mcg)+Influenza B virus B/Maryland/15/2016 BX-69A antigen (formaldehyde inactivated)(15 mcg) Injection, suspension Intramuscular; Subcutaneous SANOFİ PASTEUR AŞI TİC. A.Ş. 2020-08-14 Not applicable Turkey flag
VAXİGRİP TETRA 0,5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR , 10 ADET Influenza B virus B/Phuket/3073/2013 hemagglutinin antigen (formaldehyde inactivated)(15 mcg)+Influenza A virus A/Michigan/45/2015 X-275 (H1N1) hemagglutinin antigen (formaldehyde inactivated)(15 mcg)+甲型流感病毒A / Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (UV, formaldehyde inactivated)(15 mcg)+Influenza B virus B/Maryland/15/2016 BX-69A antigen (formaldehyde inactivated)(15 mcg) Injection, suspension Intramuscular; Subcutaneous SANOFİ PASTEUR AŞI TİC. A.Ş. 2020-08-14 Not applicable Turkey flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
9HB0XUS9TM
CAS number
Not Available

References

General References
  1. TITCK Product Information: VAXİGRİP (influenza A X-275 (H1N1), influenza A IVR-186 (H3N2), influenza B BX-69A, and influenza B) injection [Link]
Not Available

Clinical Trials

Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
4 Completed Basic Science Vaccine Reaction 1
3 Completed Prevention Influenza (Healthy Volunteers) 1
3 Terminated Prevention Influenza (Healthy Volunteers) 1
2 Completed Prevention Disease caused by Salmonella typhi 1
Not Available Completed Not Available Influenza (Healthy Volunteers) 2
Not Available Recruiting Not Available Coronavirus Disease 2019 (COVID‑19)/Influenza, Human 1
Not Available Unknown Status Not Available Obesity 1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Injection, suspension Intramuscular; Subcutaneous
Injection, suspension Intramuscular
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at July 05, 2018 18:02 / Updated at May 14, 2021 01:06