NAV

Zinc orotate

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Zinc orotateis a zinc supplement indicated in zinc deficiency.

Generic Name
Zinc orotate
DrugBank Accession Number
DB15720
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
MOL SDF PDB SMILES InChI
Similar Structures
Weight
Average: 375.56
Monoisotopic: 373.947705
Chemical Formula
C10H6N4O8Zn
Synonyms
  • Orotate zinc
  • Zinc diorotate
  • Zinc orotate

Pharmacology

Indication

Not Available

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Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
Ingredient UNII CAS InChI Key
Zinc orotate dihydrate 2R18GO895S 270083-97-1 KAXHRUFHOVCLAS-UHFFFAOYSA-L

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Z722242H10
CAS number
60388-02-5
InChI Key
YNMDOZLVAPMCBD-UHFFFAOYSA-L
InChI
InChI = 1 s / 2 c5h4n2o4.zn / c2 * 8-3-1-2 (4 (9) 10) 6 (11) 7;/h2*1H,(H,9,10)(H2,6,7,8,11);/q;;+2/p-2
IUPAC Name
锌(2 +)双(2,6-dioxo-1, 2, 3, 6-tetrahydropyrimidine-4-carboxylate)
SMILES
[Zn++].[O-]C(=O)C1=CC(=O)NC(=O)N1.[O-]C(=O)C1=CC(=O)NC(=O)N1

References

General References
  1. BASG Product Information: Zinkorotat-Pos (zinc orotate) tablet [Link]
ChemSpider
97963
RxNav
11422

Clinical Trials

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Phase Status Purpose Conditions Count

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Tablet, film coated Oral 40 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
Water Solubility 0.635 mg/mL ALOGPS
logP 0.14 ALOGPS
logP -1.2 Chemaxon
logS -2.8 ALOGPS
pKa (Strongest Acidic) 2.64 Chemaxon
pKa (Strongest Basic) -6 Chemaxon
Physiological Charge -1 Chemaxon
Hydrogen Acceptor Count 4 Chemaxon
Hydrogen Donor Count 2 Chemaxon
Polar Surface Area 98.33 Å2 Chemaxon
Rotatable Bond Count 2 Chemaxon
Refractivity 44.11 m3·mol-1 Chemaxon
Polarizability 12.01 Å3 Chemaxon
Number of Rings 2 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter No Chemaxon
Veber's Rule No Chemaxon
MDDR-like Rule No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at August 11, 2020 15:28 / Updated at May 14, 2021 01:07