NAV

Clostebol acetate

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Clostebol acetateis a steroid combined with neomycin in topical formulations for the treatment of minor skin wounds.

Generic Name
Clostebol acetate
DrugBank Accession Number
DB15984
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
 3D
Similar Structures
Weight
Average: 364.91
Monoisotopic: 364.1805225
Chemical Formula
C21H29ClO3
Synonyms
  • 4-Chlorotestosterone acetate
  • Chlorotestosterone acetate
  • Clostebol acetate
External IDs
  • 212-720-4
  • NSC-72159

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
780ZZX4P14
CAS number
855-19-6
InChI Key
XYGMEFJSKQEBTO-KUJXMBTLSA-N
InChI
InChI=1S/C21H29ClO3/c1-12(23)25-18-7-6-14-13-4-5-16-19(22)17(24)9-11-20(16,2)15(13)8-10-21(14,18)3/h13-15,18H,4-11H2,1-3H3/t13-,14-,15-,18-,20+,21-/m0/s1
IUPAC Name
(1S,3aS,3bR,9aR,9bS,11aS)-6-chloro-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
SMILES
[H][C@@]12CC[C@H](OC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=C(Cl)C(=O)CC[C@]12C

References

一般参考ences
  1. AIFA: Trofodermin (Clostebol Acetate, Neomycin Sulfate) Topical Cream [Link]
KEGG Compound
C18374
ChemSpider
12762
RxNav
236522
ChEBI
81712
ChEMBL
CHEMBL519327
ZINC
ZINC000003881980
Wikipedia
Clostebol_acetate

Clinical Trials

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Phase Status Purpose Conditions Count

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Cream Topical
Spray Cutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
Water Solubility 0.00309 mg/mL ALOGPS
logP 3.95 ALOGPS
logP 4.2 Chemaxon
logS -5.1 ALOGPS
pKa (Strongest Basic) -6.2 Chemaxon
生理上的电荷 0 Chemaxon
Hydrogen Acceptor Count 2 Chemaxon
Hydrogen Donor Count 0 Chemaxon
Polar Surface Area 43.37 Å2 Chemaxon
可旋转键数 2 Chemaxon
Refractivity 98.37 m3·mol-1 Chemaxon
Polarizability 40.68 Å3 Chemaxon
Number of Rings 4 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter Yes Chemaxon
Veber's Rule No Chemaxon
MDDR-like Rule No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at December 10, 2020 15:41 / Updated at May 07, 2021 21:09