Qutenza(R): a capsaicin 8% patch for the management of postherpetic neuralgia.
Article Details
-
Citation
Copy to clipboard -
Wallace M, Pappagallo M
Qutenza(R): a capsaicin 8% patch for the management of postherpetic neuralgia.
Expert Rev Neurother. 2011 Jan;11(1):15-27. doi: 10.1586/ern.10.182.
- PubMed ID
-
21158551 [View in PubMed]
- Abstract
-
Despite currently available treatments, postherpetic neuralgia continues to be a challenging pain condition to treat. Many patients remain in pain or suffer side effects from the (combination) therapies. A patch containing 8% capsaicin (research code NGX-4010 and marketed under the trade name Qutenza((R))), approved both in the EU and USA, provides a localized therapy with effects lasting up to 12 weeks after a single 60-min application. This review will summarize clinical trial evidence on the safety, efficacy and unique attributes of this capsaicin 8% patch in the treatment of postherpetic neuralgia. The action of capsaicin on the transient receptor potential cation channel, subfamily V, member 1 receptors will be discussed.
DrugBank Data that Cites this Article
- Drugs
- Drug Targets
-
Drug Target Kind Organism Ph值armacological Action Actions Capsaicin Transient receptor potential cation channel subfamily V member 1 Protein Humans YesAgonistRegulatorDetails