Cytochrome P-450 CYP2A6 Inhibitors (weak)

All categories
Name
Cytochrome P-450 CYP2A6 Inhibitors (weak)
Accession Number
DBCAT003897
Description

Not Available

Drugs
Drug Drug Description
Memantine An NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's.
Methimazole 一个thionamide抗甲腺的代理,可以抑制ctions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).
Cannabidiol An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
Drugs & Drug Targets
Drug Target Type
Memantine Cytochrome P450 2B6 enzyme
Memantine Solute carrier family 22 member 2 transporter
Memantine 5-hydroxytryptamine receptor 3A target
Memantine Alpha-7 nicotinic cholinergic receptor subunit target
Memantine Cytochrome P450 2A6 enzyme
Memantine Cytochrome P450 2C19 enzyme
Memantine Dopamine D2 receptor target
Memantine Glutamate receptor ionotropic, NMDA 1 target
Memantine Sodium/hydrogen exchanger 1 transporter
Memantine Solute carrier family 22 member 4 transporter
Memantine Multidrug and toxin extrusion protein 1 transporter
Memantine Glutamate (NMDA) receptor target
Memantine GABA(A) Receptor target
Memantine Glycine receptors target
Methimazole Thyroid peroxidase target
Methimazole Cytochrome P450 1A2 enzyme
Methimazole Cytochrome P450 2A6 enzyme
Methimazole Cytochrome P450 2B6 enzyme
Methimazole Cytochrome P450 2C19 enzyme
Methimazole Cytochrome P450 2C9 enzyme
Methimazole Cytochrome P450 2D6 enzyme
Methimazole Cytochrome P450 2E1 enzyme
Methimazole Cytochrome P450 3A4 enzyme
Methimazole Dimethylaniline monooxygenase [N-oxide-forming] 3 enzyme
Amphetamine Sodium-dependent dopamine transporter target
Amphetamine Cocaine- and amphetamine-regulated transcript protein target
Amphetamine Trace amine-associated receptor 1 target
Amphetamine Cytochrome P450 2D6 enzyme
Amphetamine Solute carrier family 22 member 3 transporter
Amphetamine Solute carrier family 22 member 5 transporter
Amphetamine Synaptic vesicular amine transporter target
Amphetamine Cytochrome P450 2A6 enzyme
Amphetamine Sodium-dependent noradrenaline transporter target
Amphetamine Alpha adrenergic receptor target
Amphetamine Beta adrenergic receptor target
Amphetamine Dopamine D2 receptor target
Amphetamine Amine oxidase [flavin-containing] B target
Amphetamine Sodium-dependent serotonin transporter target
Amphetamine Monoamine oxidase target
Amphetamine vesicular monoamine transporter 2 (VMAT2) target
Fenofibrate Peroxisome proliferator-activated receptor alpha target
Fenofibrate Matrix metalloproteinase-25 target
Fenofibrate Cytochrome P450 2C8 enzyme
Fenofibrate Cytochrome P450 2C9 enzyme
Fenofibrate Nuclear receptor subfamily 1 group I member 2 target
Fenofibrate UDP-glucuronosyltransferase 1-9 enzyme
Fenofibrate Bile salt export pump transporter
Fenofibrate Serum albumin carrier
Fenofibrate Cytochrome P450 2C19 enzyme
Fenofibrate Cytochrome P450 2A6 enzyme
Fenofibrate Liver carboxylesterase 1 enzyme
Fenofibrate Carbonyl reductase [NADPH] 1 enzyme
Fenofibrate Aldo-keto reductase family 1 member C1 enzyme
Fenofibrate Aldo-keto reductase family 1 member C2 enzyme
Fenofibrate Aldo-keto reductase family 1 member C3 enzyme
Fenofibrate Aldose reductase enzyme
Ethambutol Probable arabinosyltransferase B target
Ethambutol Probable arabinosyltransferase A target
Ethambutol Probable arabinosyltransferase C target
Ethambutol Cytochrome P450 1A2 enzyme
Ethambutol Cytochrome P450 2E1 enzyme
Ethambutol Cytochrome P450 2C19 enzyme
Ethambutol Cytochrome P450 2D6 enzyme
Ethambutol Cytochrome P450 2A6 enzyme
Ethambutol Cytochrome P450 2C9 enzyme
Ethambutol Cytochrome P450 3A4 enzyme
Cannabidiol Cytochrome P450 2C9 enzyme
Cannabidiol Cytochrome P450 2C19 enzyme
Cannabidiol Cytochrome P450 2D6 enzyme
Cannabidiol Cytochrome P450 3A4 enzyme
Cannabidiol Cannabinoid receptor 1 target
Cannabidiol Cannabinoid receptor 2 target
Cannabidiol G-protein coupled receptor 12 target
Cannabidiol Glycine receptor subunit alpha-1 target
Cannabidiol Glycine receptor (alpha-1/beta) target
Cannabidiol Glycine receptor subunit alpha-3 target
Cannabidiol N-arachidonyl glycine receptor target
Cannabidiol G-protein coupled receptor 55 target
Cannabidiol 5-hydroxytryptamine receptor 1A target
Cannabidiol 5-hydroxytryptamine receptor 2A target
Cannabidiol Neuronal acetylcholine receptor subunit alpha-7 target
Cannabidiol Delta-type opioid receptor target
Cannabidiol Mu-type opioid receptor target
Cannabidiol Peroxisome proliferator-activated receptor gamma target
Cannabidiol Cytochrome P450 3A5 enzyme
Cannabidiol Arylalkylamine N-acetyltransferase enzyme
Cannabidiol Cytochrome P450 1A1 enzyme
Cannabidiol Fatty-acid amide hydrolase 1 enzyme
Cannabidiol Arachidonate 5-lipoxygenase enzyme
Cannabidiol Arachidonate 15-lipoxygenase enzyme
Cannabidiol Quinone oxidoreductase enzyme
Cannabidiol Multidrug resistance-associated protein 1 transporter
Cannabidiol ATP-binding cassette sub-family G member 2 transporter
Cannabidiol Equilibrative nucleoside transporter 1 transporter
Cannabidiol Transient receptor potential cation channel subfamily V member 1 target
Cannabidiol Voltage-dependent T-type calcium channel subunit alpha-1G target
Cannabidiol Voltage-dependent T-type calcium channel subunit alpha-1H target
Cannabidiol Voltage-dependent T-type calcium channel subunit alpha-1I target
Cannabidiol Transient receptor potential cation channel subfamily A member 1 target
Cannabidiol Transient receptor potential cation channel subfamily M member 8 target
Cannabidiol Transient receptor potential cation channel subfamily V member 2 target
Cannabidiol Transient receptor potential cation channel subfamily V member 3 target
Cannabidiol Transient receptor potential cation channel subfamily V member 4 target
Cannabidiol Voltage-dependent anion-selective channel protein 1 target
Cannabidiol 5-hydroxytryptamine receptor 3A target
Cannabidiol Adenosine receptor A1 target
Cannabidiol Prostaglandin G/H synthase 1 target
Cannabidiol Prostaglandin G/H synthase 2 target
Cannabidiol Acetyl-CoA acetyltransferase, mitochondrial target
Cannabidiol Steroid 17-alpha-hydroxylase/17,20 lyase target
Cannabidiol 3-hydroxy-3-methylglutaryl-coenzyme A reductase target
Cannabidiol Glutathione reductase, mitochondrial target
Cannabidiol Glutathione peroxidase 1 target
Cannabidiol Indoleamine 2,3-dioxygenase 1 target
Cannabidiol Cytochrome P450 1B1 target
Cannabidiol NAD(P)H dehydrogenase [quinone] 1 target
Cannabidiol Catalase target
Cannabidiol Cytochrome P450 3A5 target
Cannabidiol Cytochrome P450 2D6 target
Cannabidiol Superoxide dismutase [Cu-Zn] target
Cannabidiol Cytochrome P450 1A2 target
Cannabidiol Cytochrome P450 3A7 target
Cannabidiol Arylalkylamine N-acetyltransferase target
Cannabidiol N-acylethanolamine-hydrolyzing acid amidase target
Cannabidiol Cytochrome P450 1A2 enzyme
Cannabidiol Cytochrome P450 1B1 enzyme
Cannabidiol Cytochrome P450 2A6 enzyme
Cannabidiol Cytochrome P450 2B6 enzyme
Cannabidiol Cytochrome P450 2C8 enzyme
Cannabidiol Cytochrome P450 2E1 enzyme
Cannabidiol Cytochrome P450 3A7 enzyme
Cannabidiol UDP-glucuronosyltransferase 1-7 enzyme
Cannabidiol UDP-glucuronosyltransferase 1-9 enzyme
Cannabidiol UDP-glucuronosyltransferase 2B7 enzyme
Cannabidiol UDP-glucuronosyltransferase 2B17 enzyme
Cannabidiol P-glycoprotein 1 transporter
Cannabidiol Cytochrome P450 2J2 enzyme
Cannabidiol Liver carboxylesterase 1 enzyme