NAV

Boron

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Boron
DrugBank Accession Number
DB11203
Background

Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard to prepare due to contamination by different elements. It is also found for applications including ceramics, high-hardness or abrasive compounds, metal coatings, detergents, bleaching agents, insecticides, semiconductors, magnets, wood preservatives, and an additive in glass fibers of boron-containing fiberglass for insulation and structural materials. Boric acid contains antiseptic, antifungal, and antiviral properties thus it is used as a water clarifier in swimming pool water treatment. There are few pharmaceutical agents that contain a boron molecule in their structures, such asTavaboroleandBortezomib.

Type
Small Molecule
Groups
Experimental
Structure
MOL SDF PDB SMILES InChI
Similar Structures
Weight
Average: 10.81
Monoisotopic: 11.009305
Chemical Formula
B
Synonyms
  • Bor
  • Boracium
  • Bore
  • Boro

Pharmacology

Indication

Not Available

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Associated Conditions
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Not Available

Interactions

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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image
Calcemin Boron(50 ug/1)+Previtamin D(3)(0.75 mg/1)+Zinc(2 mg/1) Tablet, film coated Oral 湾er Healthcare Llc. 2016-04-01 Not applicable US flag
Calcemin Silver Boron(2.6 mg/1)+Magnesium oxide(40 mg/1)+Zinc oxide(7.5 mg/1) Tablet, film coated Oral 湾er Healthcare Llc. 2016-04-01 Not applicable US flag
MENOPACE KAPSUL, 30 ADET Boron(2 mg)+Aminobenzoic acid(30 mg)+Ascorbic acid(45 mg)+Biotin(30 mcg)+Chromium picolinate(50 mcg)+Copper(1 mg)+Cyanocobalamin(9 mcg)+Folic acid(400 mcg)+Iodine(225 mcg)+Iron(12 mg)+Magnesium(100 mg)+Manganese(2 mg)+Niacin(20 mg)+Pantothenic acid(30 mg)+Pyridoxine(40 mg)+Riboflavin(5 mg)+Selenium(100 mcg)+Thiamine(10 mg)+Vitamin A(750 mcg)+Vitamin D(2.5 mcg)+Vitamin E(30 mg)+Zinc(15 mg) Capsule Oral NOBEL İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 2020-05-28 Turkey flag
Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image
Calcium Folic Acid Plus D Chewable Boron(250 ug/1)+Calcium carbonate(1342 mg/1)+Cholecalciferol(300 [iU]/1)+Cyanocobalamin(125 ug/1)+Folic acid(1 mg/1)+Magnesium(50 mg/1)+Pyridoxine(10 mg/1) Wafer Oral Acella Pharmaceuticals, LLC 2009-03-20 2022-08-02 US flag
Foliflex Boron(25 ug/1)+Ascorbic acid(250 mg/1)+Biotin(100 ug/1)+Calcium carbonate(75 mg/1)+Cholecalciferol(13.75 ug/1)+Chromium nicotinate(37.5 ug/1)+Cupric oxide(1 mg/1)+Cyanocobalamin(13 ug/1)+DL-alpha tocopheryl acetate(45 mg/1)+Ferrous fumarate(9 mg/1)+Folic acid(500 ug/1)+Magnesium oxide(37.5 mg/1)+Manganese sulfate(0.75 mg/1)+Molybdenum(25 ug/1)+Nicotinamide(22.5 mg/1)+Pantothenic acid(15 mg/1)+Potassium Iodide(25 ug/1)+Potassium chloride(24.5 mg/1)+Pyridoxine hydrochloride(6 mg/1)+Riboflavin(3.35 mg/1)+Selenium(30 ug/1)+Thiamine mononitrate(3.25 mg/1)+Vitamin A acetate(1500 ug/1)+Zinc oxide(15 mg/1) Tablet Oral PureTek Corporation 2021-10-25 Not applicable US flag
Folitin-Z Boron(25 ug/1)+Ascorbic acid(250 mg/1)+Biotin(100 ug/1)+Calcium carbonate(75 mg/1)+Cholecalciferol(13.75 ug/1)+Chromium nicotinate(37.5 ug/1)+Cupric oxide(1 mg/1)+Cyanocobalamin(13 ug/1)+DL-alpha tocopheryl acetate(45 mg/1)+Ferrous fumarate(9 mg/1)+Folic acid(500 ug/1)+Magnesium oxide(37.5 mg/1)+Manganese sulfate(0.75 mg/1)+Molybdenum(25 ug/1)+Nicotinamide(22.5 mg/1)+Pantothenic acid(15 mg/1)+Potassium Iodide(25 ug/1)+Potassium chloride(24.5 mg/1)+Pyridoxine hydrochloride(6 mg/1)+Riboflavin(3.35 mg/1)+Selenium(30 ug/1)+Thiamine mononitrate(3.25 mg/1)+Vitamin A acetate(1500 ug/1)+Zinc oxide(15 mg/1) Tablet Oral PureTek Corporation 2021-02-11 Not applicable US flag
Neonatal Plus Vitamin Boron(0.2 mg/1)+Ascorbic acid(20 mg/1)+Calcium(200 mg/1)+Cholecalciferol(10 ug/1)+Citrus bioflavonoids(2 mg/1)+Copper(2 mg/1)+Cyanocobalamin(12 ug/1)+Ferrous fumarate(27 mg/1)+Folic acid(1000 ug/1)+Inositol(5 mg/1)+Nicotinamide(20 mg/1)+Pyridoxine hydrochloride(10 mg/1)+Riboflavin(3 mg/1)+Thiamine chloride(1.84 mg/1)+Vitamin A(1200 ug/1)+Zinc oxide(25 mg/1)+alpha-Tocopherol acetate(9.2 mg/1) Tablet Oral Neomed Pharmaceutical 2018-07-31 Not applicable US flag
Prenate Chewable Boron(250 ug/1)+Bilberry(25 mg/1)+Biotin(280 ug/1)+Calcium carbonate(500 mg/1)+Cholecalciferol(300 [iU]/1)+Cyanocobalamin(125 mg/1)+Folic acid(1 mg/1)+Magnesium oxide(50 mg/1)+Pyridoxine hydrochloride(10 mg/1) Tablet, chewable Oral Avion Pharmaceuticals, Llc 2013-01-16 Not applicable US flag
Ribotin-E Boron(25 ug/1)+Ascorbic acid(250 mg/1)+Biotin(100 ug/1)+Calcium carbonate(75 mg/1)+Cholecalciferol(13.75 ug/1)+Chromium nicotinate(37.5 ug/1)+Cupric oxide(1 mg/1)+Cyanocobalamin(13 ug/1)+DL-alpha tocopheryl acetate(45 mg/1)+Ferrous fumarate(9 mg/1)+Folic acid(500 ug/1)+Magnesium oxide(37.5 mg/1)+Manganese sulfate(0.75 mg/1)+Molybdenum(25 ug/1)+Nicotinamide(22.5 mg/1)+Pantothenic acid(15 mg/1)+Potassium Iodide(25 ug/1)+Potassium chloride(24.5 mg/1)+Pyridoxine hydrochloride(6 mg/1)+Riboflavin(3.35 mg/1)+Selenium(30 ug/1)+Thiamine mononitrate(3.25 mg/1)+Vitamin A acetate(1500 ug/1)+Zinc oxide(15 mg/1) Tablet Oral PureTek Corporation 2021-02-11 Not applicable US flag
Zintrexyl-C Boron(25 ug/1)+Ascorbic acid(250 mg/1)+Biotin(100 ug/1)+Calcium carbonate(75 mg/1)+Cholecalciferol(13.75 ug/1)+Chromium nicotinate(37.5 ug/1)+Cupric oxide(1 mg/1)+Cyanocobalamin(13 ug/1)+DL-alpha tocopheryl acetate(45 mg/1)+Ferrous fumarate(9 mg/1)+Folic acid(500 ug/1)+Magnesium oxide(37.5 mg/1)+Manganese sulfate(0.75 mg/1)+Molybdenum(25 ug/1)+Nicotinamide(22.5 mg/1)+Pantothenic acid(15 mg/1)+Potassium Iodide(25 ug/1)+Potassium chloride(24.5 mg/1)+Pyridoxine hydrochloride(6 mg/1)+Riboflavin(3.35 mg/1)+Selenium(30 ug/1)+Thiamine mononitrate(3.25 mg/1)+Vitamin A acetate(1500 ug/1)+Zinc oxide(15 mg/1) Tablet Oral PureTek Corporation 2021-02-11 Not applicable US flag

Categories

Drug Categories
Chemical TaxonomyProvided byClassyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous metalloid compounds
Sub Class
Not Available
Direct Parent
Homogeneous metalloid compounds
Alternative Parents
Not Available
Substituents
Homogeneous metalloid
Molecular Framework
Not Available
External Descriptors
boron group element atom, nonmetal atom (CHEBI:27560)
Affected organisms
Not Available

Chemical Identifiers

UNII
N9E3X5056Q
CAS number
7440-42-8
InChI Key
ZOXJGFHDIHLPTG-UHFFFAOYSA-N
InChI
InChI = 1 s / B
IUPAC Name
boranylidyne
SMILES
[B]

References

一般引用
Not Available
PubChem Compound
5462311
PubChem Substance
347827941
ChemSpider
4575371
RxNav
1705
ChEBI
27560
Wikipedia
Boron

Clinical Trials

Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
3 Completed Treatment Radiodermatitis 1
2 Active Not Recruiting Treatment Advanced Malignant Solid Tumor/Recurrent Malignant Solid Neoplasm 1
1 Terminated Treatment Central Nervous System Neoplasm 1
1 Unknown Status Treatment Diabetic Foot Ulcers (DFUs) 1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Capsule Oral
Tablet, film coated Oral
Wafer Oral
Tablet Oral
Tablet, chewable Oral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
logP 0.33 Chemaxon
Physiological Charge 0 Chemaxon
Hydrogen Acceptor Count 0 Chemaxon
Hydrogen Donor Count 0 Chemaxon
Polar Surface Area 0 Å2 Chemaxon
Rotatable Bond Count 0 Chemaxon
Refractivity 0 m3·mol-1 Chemaxon
Polarizability 1.78 Å3 Chemaxon
Number of Rings 0 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter No Chemaxon
Veber's Rule Yes Chemaxon
MDDR-like Rule No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Spectrum Spectrum Type Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available

Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54