Glycosaminoglycans

Name
Glycosaminoglycans
Accession Number
DBCAT001272
Description

Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.

Drugs
Drug Drug Description
Ardeparin For prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery.
Heparin An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
Enoxaparin A low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction.
Semuloparin Investigated for use/treatment in thrombosis.
Danaparoid A heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT.
Dalteparin A low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
Tinzaparin A low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin.
Nadroparin A low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
Hyaluronic acid 一个用于th粘多糖e relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
Bemiparin An ultra-low molecular weight heparin (ultra-LMWH) used to prevent thromboembolism following surgery and extracorporeal clotting during dialysis.
Reviparin By the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of...
Parnaparin A low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
Certoparin A low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
Chondroitin sulfate Chondroitin sulfate, used with glucosamine, is indicated to alleviate pain and inflammation from primary osteoarthritis. This supplement is reported to improve joint function and slow disease progression. Osteoarthritis is characterized...
Antithrombin III human An alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
Pentosan polysulfate A sulfated pentosyl polysaccharide used to treat bladder pain and discomfort due to interstitial cystitis.
Sevuparin Sevuparin is under investigation in clinical trial NCT03853421 (Placebo-controlled Study to Determine the Safety and Tolerability of Subcutaneous Doses of Sevuparin).
Dermatan sulfate A medication indicated to prevent deep vein thrombosis.
Dociparstat sodium Not Available
Roneparstat Not Available
Drugs & Drug Targets
Drug Target Type
Ardeparin Heparin cofactor 2 target
Ardeparin Antithrombin-III target
Heparin Antithrombin-III target
Heparin Coagulation factor X target
Heparin P-selectin target
Heparin Heparanase enzyme
Heparin Fibroblast growth factor receptor 4 target
Heparin Fibroblast growth factor 4 target
Heparin Fibroblast growth factor 19 target
Heparin Fibroblast growth factor receptor 1 target
Heparin Fibroblast growth factor 1 target
Heparin Fibroblast growth factor receptor 2 target
Heparin Fibroblast growth factor 2 target
Heparin Platelet factor 4 target
Heparin Hepatocyte growth factor target
Heparin Thyroxine-binding globulin carrier
Enoxaparin Antithrombin-III target
Enoxaparin Coagulation factor X target
Enoxaparin Myeloperoxidase enzyme
Enoxaparin Prothrombin target
Danaparoid Antithrombin-III target
Dalteparin Vascular endothelial growth factor A target
Dalteparin Tissue factor pathway inhibitor target
Dalteparin Heparanase enzyme
Dalteparin Antithrombin-III target
Dalteparin P-selectin target
Tinzaparin Antithrombin-III target
Tinzaparin A disintegrin and metalloproteinase with thrombospondin motifs 4 enzyme
Tinzaparin Integrin alpha-4 target
Tinzaparin Stromal cell-derived factor 1 target
Nadroparin Proto-oncogene c-Fos target
Nadroparin Myc proto-oncogene protein target
Nadroparin P-selectin target
Nadroparin Antithrombin-III target
Hyaluronic acid CD44 antigen target
Hyaluronic acid Intercellular adhesion molecule 1 target
Hyaluronic acid Hyaluronan mediated motility receptor target
Hyaluronic acid Neurocan core protein target
Hyaluronic acid Versican core protein target
Hyaluronic acid Complement component 1 Q subcomponent-binding protein, mitochondrial target
Hyaluronic acid Hyaluronan and proteoglycan link protein 1 target
Hyaluronic acid Hyaluronan and proteoglycan link protein 3 target
Hyaluronic acid Hyaluronan-binding protein 2 target
Hyaluronic acid Layilin target
Hyaluronic acid Stabilin-2 target
Hyaluronic acid Tumor necrosis factor-inducible gene 6 protein target
Hyaluronic acid Interphotoreceptor matrix proteoglycan 2 target
Hyaluronic acid Intracellular hyaluronan-binding protein 4 target
Hyaluronic acid Hyaluronidase enzymes enzyme
Hyaluronic acid Multidrug resistance-associated protein 5 transporter
Hyaluronic acid Lymphatic vessel endothelial hyaluronic acid receptor 1 target
Bemiparin Coagulation factor X target
Bemiparin Antithrombin-III target
Bemiparin Heparin cofactor 2 target
Chondroitin sulfate Brain-derived neurotrophic factor target
Chondroitin sulfate Glial cell line-derived neurotrophic factor target
Chondroitin sulfate Vascular endothelial growth factor A target
Chondroitin sulfate C-C motif chemokine 2 target
Chondroitin sulfate Beta-glucuronidase enzyme
Chondroitin sulfate Beta-hexosaminidase subunit beta enzyme
Chondroitin sulfate N-acetylgalactosamine-6-sulfatase enzyme
Chondroitin sulfate Iduronate 2-sulfatase enzyme
Chondroitin sulfate Alpha-L-iduronidase enzyme
Chondroitin sulfate Arylsulfatase B enzyme
Antithrombin III human Antithrombin-III target
Pentosan polysulfate Fibroblast growth factor 1 target
Pentosan polysulfate Fibroblast growth factor 4 target
Pentosan polysulfate Fibroblast growth factor 2 target