Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates

Name
Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
Accession Number
DBCAT004539
Description

This category has been created to cover the interactions between monoamine oxidase A (MAO-A) substrates and MAO-A inhibitors. This "inhibitors" category is separate from the originally created, "Monoamine Oxidase A Inhibitors" category, which could not be used due to interference with the parent category, "Antidepressant Agents", which contains both MAO type A and B inhibitors. This category is specifically for interactions between MAO-A substrates and inhibitors.

Drugs
Drug Drug Description
Moclobemide 本文中使用的单胺氧化酶抑制剂t of major depressive disorder and bipolar disorder.
Isocarboxazid A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
Tranylcypromine A monoamine oxidase inhibitor used to treat major depressive disorder.
Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
Linezolid An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
Phentermine A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity.
Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
Zonisamide A sulfonamide anticonvulsant used to treat partial seizures.
Minaprine For the treatment of depression
Pargyline For the treatment of moderate to severe hypertension.
4-Methoxyamphetamine Not Available
Ephedra sinica root An alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
MMDA MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present.
Metamfetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity.
Nicotine A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
Furazolidone A drug for the treatment of infectious diarrhea.
Zimelidine For the treatment of depression.
Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
Nandrolone decanoate An anabolic steroid indicated for the management of the anemia of renal insufficiency by increasing hemoglobin and red cell mass.
Safinamide A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
Brofaromine Not Annotated
Toloxatone For the treatment of major depressive disorder.
Pirlindole For the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving...
Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
Iproniazid For the treatment of depression (originally intended to treat tuberculosis).
Ubrogepant An oral CGRP antagonist used in the acute treatment of migraine with or without aura.
Tedizolid An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.
Tedizolid phosphate An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.
Ginkgo biloba A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders.
Viloxazine A selective norepinephrine reuptake inhibitor indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adults in children.
Drugs & Drug Targets
Drug Target Type
Moclobemide Amine oxidase [flavin-containing] A target
Moclobemide Cytochrome P450 2C19 enzyme
Moclobemide Cytochrome P450 2D6 enzyme
Moclobemide Amine oxidase [flavin-containing] A enzyme
Moclobemide Amine oxidase [flavin-containing] B enzyme
Moclobemide Cytochrome P450 2C9 enzyme
Moclobemide Monoamine oxidase target
Moclobemide Amine oxidase [flavin-containing] B target
Isocarboxazid Amine oxidase [flavin-containing] A target
Isocarboxazid Amine oxidase [flavin-containing] B target
Tranylcypromine Amine oxidase [flavin-containing] B target
Tranylcypromine Amine oxidase [flavin-containing] A target
Tranylcypromine Cytochrome P450 2C19 enzyme
Tranylcypromine Cytochrome P450 2A6 enzyme
Tranylcypromine Cytochrome P450 2D6 enzyme
Tranylcypromine Cytochrome P450 1A2 enzyme
Tranylcypromine Cytochrome P450 2C9 enzyme
Tranylcypromine Cytochrome P450 3A4 enzyme
Phenylpropanolamine Amine oxidase [flavin-containing] A enzyme
Phenylpropanolamine Dopamine D1 receptor target
Phenylpropanolamine Beta-1 adrenergic receptor target
Phenylpropanolamine Beta-2 adrenergic receptor target
Phenylpropanolamine Alpha-2 adrenergic receptors target
Pseudoephedrine Alpha-1A adrenergic receptor target
Pseudoephedrine Alpha-2A adrenergic receptor target
Pseudoephedrine Beta-2 adrenergic receptor target
Pseudoephedrine Amine oxidase [flavin-containing] A enzyme
Pseudoephedrine Beta-1 adrenergic receptor target
Pseudoephedrine Sodium-dependent dopamine transporter target
Pseudoephedrine Sodium-dependent noradrenaline transporter target
Pseudoephedrine Sodium-dependent serotonin transporter target
Pseudoephedrine Nuclear factor of activated T-cells, cytoplasmic 1 target
Pseudoephedrine Tumor necrosis factor target
Pseudoephedrine Nuclear factor NF-kappa-B p105 subunit target
Pseudoephedrine activator protein 1 target
Pseudoephedrine Interleukin-2 target
Pseudoephedrine Serum albumin carrier
Pseudoephedrine Sodium-dependent noradrenaline transporter transporter
Pseudoephedrine Sodium-dependent dopamine transporter transporter
Pseudoephedrine Sodium-dependent serotonin transporter transporter
Linezolid 23S ribosomal RNA target
Linezolid Amine oxidase [flavin-containing] A enzyme
Linezolid Amine oxidase [flavin-containing] B enzyme
Linezolid Serum albumin carrier
Linezolid 溶解te carrier family 22 member 6 transporter
Linezolid 溶解te carrier family 22 member 8 transporter
Phentermine Sodium-dependent noradrenaline transporter target
Phentermine Sodium-dependent dopamine transporter target
Phentermine Amine oxidase [flavin-containing] A target
Phentermine Amine oxidase [flavin-containing] B target
Phentermine Sodium-dependent serotonin transporter target
Phentermine Pro-neuropeptide Y target
Phentermine Cytochrome P450 3A4 enzyme
Selegiline Amine oxidase [flavin-containing] B target
Selegiline Cytochrome P450 2B6 enzyme
Selegiline Amine oxidase [flavin-containing] A target
Selegiline Cytochrome P450 2A6 enzyme
Selegiline Cytochrome P450 3A4 enzyme
Selegiline P-glycoprotein 1 transporter
Selegiline Cytochrome P450 1A2 enzyme
Selegiline Cytochrome P450 2C19 enzyme
Selegiline Cytochrome P450 2C8 enzyme
Selegiline Cytochrome P450 2C9 enzyme
Selegiline Cytochrome P450 2D6 enzyme
Zonisamide Sodium channel protein type 1 subunit alpha target
Zonisamide Carbonic anhydrase 1 target
Zonisamide Voltage-dependent T-type calcium channel subunit alpha-1G target
Zonisamide Cytochrome P450 3A4 enzyme
Zonisamide Aldehyde oxidase enzyme
Zonisamide Amine oxidase [flavin-containing] B target
Zonisamide Carbonic anhydrase 2 target
Zonisamide Carbonic anhydrase 3 target
Zonisamide Carbonic anhydrase 4 target
Zonisamide Carbonic anhydrase 5A, mitochondrial target
Zonisamide Carbonic anhydrase 5B, mitochondrial target
Zonisamide Carbonic anhydrase 6 target
Zonisamide Carbonic anhydrase 7 target
Zonisamide Carbonic anhydrase-related protein target
Zonisamide Carbonic anhydrase 9 target
Zonisamide Carbonic anhydrase-related protein 10 target
Zonisamide Carbonic anhydrase-related protein 11 target
Zonisamide Carbonic anhydrase 12 target
Zonisamide Carbonic anhydrase 13 target
Zonisamide Carbonic anhydrase 14 target
Zonisamide Voltage-dependent T-type calcium channel subunit alpha-1H target
Zonisamide Voltage-dependent T-type calcium channel subunit alpha-1I target
Zonisamide Sodium channel protein type 2 subunit alpha target
Zonisamide Sodium channel protein type 3 subunit alpha target
Zonisamide Sodium channel protein type 4 subunit alpha target
Zonisamide Sodium channel protein type 5 subunit alpha target
Zonisamide Sodium channel protein type 9 subunit alpha target
Zonisamide Sodium channel protein type 11 subunit alpha target
Zonisamide Sodium channel subunit beta-1 target
Zonisamide Sodium channel subunit beta-2 target
Zonisamide Sodium channel subunit beta-3 target
Zonisamide Sodium channel subunit beta-4 target
Zonisamide Amine oxidase [flavin-containing] A target
Zonisamide Cytochrome P450 2C19 enzyme
Zonisamide UDP-glucuronosyltransferase 1-1 enzyme
Zonisamide Cytochrome P450 3A5 enzyme
Zonisamide P-glycoprotein 1 transporter
Zonisamide GABA(A) Receptor Benzodiazepine Binding Site target
Minaprine Dopamine D1 receptor target
Minaprine Dopamine D2 receptor target
Minaprine 5-hydroxytryptamine receptor 2A target
Minaprine 5-hydroxytryptamine receptor 2B target
Minaprine 5-hydroxytryptamine receptor 2C target
Minaprine Sodium-dependent serotonin transporter target
Minaprine Cytochrome P450 2D6 enzyme
Minaprine Muscarinic acetylcholine receptor M1 target
Minaprine Acetylcholinesterase target
Minaprine Amine oxidase [flavin-containing] A target
Pargyline Amine oxidase [flavin-containing] B target
Pargyline Amine oxidase [flavin-containing] A target
4-Methoxyamphetamine Alpha-1A adrenergic receptor target
4-Methoxyamphetamine Alpha-2A adrenergic receptor target
4-Methoxyamphetamine Cytochrome P450 2D6 enzyme
4-Methoxyamphetamine Sodium-dependent dopamine transporter target
4-Methoxyamphetamine Sodium-dependent serotonin transporter target
4-Methoxyamphetamine Amine oxidase [flavin-containing] A target
4-Methoxyamphetamine Amine oxidase [flavin-containing] B target
4-Methoxyamphetamine Synaptic vesicular amine transporter target
Ephedra sinica root Sodium-dependent dopamine transporter target
Ephedra sinica root Synaptic vesicular amine transporter target
Ephedra sinica root Chromaffin granule amine transporter target
Ephedra sinica root Sodium-dependent noradrenaline transporter target
Ephedra sinica root Amine oxidase [flavin-containing] A target
Ephedra sinica root Amine oxidase [flavin-containing] B target
Ephedra sinica root Sodium-dependent serotonin transporter target
Ephedra sinica root Alpha-2A adrenergic receptor target
Ephedra sinica root Alpha-2B adrenergic receptor target
Ephedra sinica root Alpha-2C adrenergic receptor target
Ephedra sinica root Beta-1 adrenergic receptor target
Ephedra sinica root Beta-2 adrenergic receptor target
Ephedra sinica root Beta-3 adrenergic receptor target
MMDA 5-hydroxytryptamine receptor 2A target
MMDA Sodium-dependent serotonin transporter target
MMDA Sodium-dependent dopamine transporter target
MMDA Chromaffin granule amine transporter target
MMDA Synaptic vesicular amine transporter target
MMDA Amine oxidase [flavin-containing] A target
MMDA Amine oxidase [flavin-containing] B target
MMDA Sodium-dependent noradrenaline transporter target
Metamfetamine Cytochrome P450 2D6 enzyme
Metamfetamine 溶解te carrier family 22 member 3 transporter
Metamfetamine 溶解te carrier family 22 member 5 transporter
Metamfetamine Sodium-dependent dopamine transporter target
Metamfetamine Synaptic vesicular amine transporter target
Metamfetamine Trace amine-associated receptor 1 target
Metamfetamine Sodium-dependent serotonin transporter target
Metamfetamine Sodium-dependent noradrenaline transporter target
Metamfetamine Chromaffin granule amine transporter target
Metamfetamine Amine oxidase [flavin-containing] A target
Metamfetamine Amine oxidase [flavin-containing] B target
Metamfetamine Alpha-2A adrenergic receptor target
Metamfetamine Alpha-2B adrenergic receptor target
Metamfetamine Alpha-2C adrenergic receptor target
Nicotine Neuronal acetylcholine receptor subunit alpha-2 target
Nicotine Neuronal acetylcholine receptor subunit beta-2 target
Nicotine Neuronal acetylcholine receptor subunit alpha-7 target
Nicotine Neuronal acetylcholine receptor subunit alpha-4 target
Nicotine Neuronal acetylcholine receptor subunit alpha-10 target
Nicotine Neuronal acetylcholine receptor subunit alpha-9 target
Nicotine Cytochrome P450 2A6 enzyme
Nicotine Cytochrome P450 2E1 enzyme
Nicotine Cytochrome P450 2A13 enzyme
Nicotine Cytochrome P450 2B6 enzyme
Nicotine Neuronal acetylcholine receptor subunit beta-4 target
Nicotine Neuronal acetylcholine receptor subunit alpha-3 target
Nicotine Neuronal acetylcholine receptor subunit alpha-5 target
Nicotine Neuronal acetylcholine receptor subunit alpha-6 target
Nicotine Neuronal acetylcholine receptor subunit beta-3 target
Nicotine 溶解te carrier family 22 member 2 transporter
Nicotine 溶质载体家庭22个成员1 transporter
Nicotine 溶解te carrier family 22 member 3 transporter
Nicotine 溶解te carrier family 22 member 5 transporter
Nicotine 溶解te carrier family 22 member 4 transporter
Nicotine Cytochrome P450 1A1 enzyme
Nicotine Cytochrome P450 1A2 enzyme
Nicotine Cytochrome P450 2C19 enzyme
Nicotine Cytochrome P450 2C8 enzyme
Nicotine Cytochrome P450 2C9 enzyme
Nicotine Cytochrome P450 2D6 enzyme
Nicotine Cytochrome P450 3A4 enzyme
Nicotine Amine oxidase [flavin-containing] A enzyme
Nicotine Amine oxidase [flavin-containing] B enzyme
Nicotine Cytochrome P450 19A1 target
Nicotine Choline O-acetyltransferase target
Furazolidone DNA target
Furazolidone Amine oxidase [flavin-containing] B enzyme
Furazolidone Amine oxidase [flavin-containing] A enzyme
Zimelidine Sodium-dependent serotonin transporter target
Zimelidine P-glycoprotein 1 transporter
Zimelidine Amine oxidase [flavin-containing] B target
Zimelidine Amine oxidase [flavin-containing] A target
Zimelidine Cytochrome P450 3A4 enzyme
Capsaicin Cytochrome P450 3A4 enzyme
Capsaicin Prostaglandin G/H synthase 2 enzyme
Capsaicin Myeloperoxidase enzyme
Capsaicin Cytochrome P450 1A2 enzyme
Capsaicin Cytochrome P450 2E1 enzyme
Capsaicin Amine oxidase [flavin-containing] A enzyme
Capsaicin Dopamine beta-hydroxylase enzyme
Capsaicin Glutamine synthetase enzyme
Capsaicin Cholinesterase enzyme
Capsaicin Transient receptor potential cation channel subfamily V member 1 target
Capsaicin Prohibitin-2 target
Nandrolone decanoate Androgen receptor target
Nandrolone decanoate Cytochrome P450 19A1 enzyme
Nandrolone decanoate Amine oxidase [flavin-containing] B enzyme
Nandrolone decanoate Amine oxidase [flavin-containing] A enzyme
Nandrolone decanoate Proto-oncogene c-Fos target
Nandrolone decanoate 5-hydroxytryptamine 2 receptor target
Nandrolone decanoate 5-hydroxytryptamine receptor 1B target
Nandrolone decanoate Insulin-like growth factor 1 receptor target
Nandrolone decanoate Dopamine receptor target
Nandrolone decanoate UDP-glucuronosyltransferase 2B7 enzyme
Nandrolone decanoate UDP-glucuronosyltransferase 1-4 enzyme
Nandrolone decanoate UDP-glucuronosyltransferase 2B4 enzyme
Nandrolone decanoate UDP-glucuronosyltransferase 1-3 enzyme
Nandrolone decanoate UDP-glucuronosyltransferase 1-1 enzyme
Nandrolone decanoate UDP-glucuronosyltransferase 1-10 enzyme
Nandrolone decanoate Sex hormone-binding globulin carrier
Safinamide Amine oxidase [flavin-containing] B target
Safinamide Amine oxidase [flavin-containing] A enzyme
Safinamide ATP-binding cassette sub-family G member 2 transporter
Safinamide 溶解te carrier organic anion transporter family member 3A1 transporter
Safinamide Cytochrome P450 3A4 enzyme
Safinamide Cytochrome P450 1A1 enzyme
Safinamide Cytochrome P450 1A2 enzyme
Safinamide Cytochrome P450 2D6 enzyme
Safinamide Cytochrome P450 2C19 enzyme
Safinamide Cytochrome P450 3A5 enzyme
Brofaromine Amine oxidase [flavin-containing] A target
Toloxatone Amine oxidase [flavin-containing] A target
Toloxatone Amine oxidase [flavin-containing] A enzyme
Pirlindole Amine oxidase [flavin-containing] A target
Pirlindole 5-hydroxytryptamine receptor 1A target
Pirlindole Alpha-2A adrenergic receptor target
Pirlindole Amine oxidase [flavin-containing] A enzyme
Propranolol Beta-1 adrenergic receptor target
Propranolol Beta-2 adrenergic receptor target
Propranolol Beta-3 adrenergic receptor target
Propranolol 5-hydroxytryptamine receptor 1A target
Propranolol 5-hydroxytryptamine receptor 1B target
Propranolol Cytochrome P450 1A2 enzyme
Propranolol Cytochrome P450 2D6 enzyme
Propranolol Alpha-1-acid glycoprotein 1 carrier
Propranolol Cytochrome P450 2C19 enzyme
Propranolol Cytochrome P450 3A4 enzyme
Propranolol Cytochrome P450 3A5 enzyme
Propranolol Cytochrome P450 3A7 enzyme
Propranolol 溶解te carrier family 22 member 2 transporter
Propranolol P-glycoprotein 1 transporter
Propranolol Cytochrome P450 1A1 enzyme
Propranolol Amine oxidase [flavin-containing] A enzyme
Propranolol Serum albumin carrier
Iproniazid Amine oxidase [flavin-containing] B enzyme
Iproniazid Cytochrome P450 2D6 enzyme
Iproniazid Cytochrome P450 2C9 enzyme
Iproniazid Amine oxidase [flavin-containing] A enzyme
Ubrogepant P-glycoprotein 1 transporter
Ubrogepant ATP-binding cassette sub-family G member 2 transporter
Ubrogepant Cytochrome P450 3A4 enzyme
Ubrogepant Cytochrome P450 2C8 enzyme
Ubrogepant Cytochrome P450 2C9 enzyme
Ubrogepant Cytochrome P450 2D6 enzyme
Ubrogepant Cytochrome P450 2C19 enzyme
Ubrogepant Amine oxidase [flavin-containing] A enzyme
Ubrogepant UDP-glucuronosyltransferase 1-1 enzyme
Ubrogepant 溶解te carrier organic anion transporter family member 1B1 transporter
Ubrogepant 溶解te carrier organic anion transporter family member 1B3 transporter
Ubrogepant 溶解te carrier family 22 member 6 transporter
Ubrogepant 溶解te carrier family 22 member 2 transporter
Ubrogepant Calcitonin gene-related peptide type 1 receptor target
Tedizolid 23S ribosomal RNA target
Tedizolid Amine oxidase [flavin-containing] A enzyme
Tedizolid Amine oxidase [flavin-containing] B enzyme
Tedizolid phosphate 23S ribosomal RNA target
Tedizolid phosphate Amine oxidase [flavin-containing] A enzyme
Tedizolid phosphate Amine oxidase [flavin-containing] B enzyme
Ginkgo biloba Cytochrome P450 2C9 enzyme
Ginkgo biloba Phospholipase A2, membrane associated target
Ginkgo biloba Sodium-dependent noradrenaline transporter target
Ginkgo biloba Glycine receptor subunit alpha-1 target
Ginkgo biloba Gamma-aminobutyric acid receptor subunit alpha-1 target
Ginkgo biloba Gamma-aminobutyric acid receptor subunit beta-2 target
Ginkgo biloba Gamma-aminobutyric acid receptor subunit gamma-2 target
Ginkgo biloba Cytochrome P450 3A4 enzyme
Ginkgo biloba Amine oxidase [flavin-containing] A target
Ginkgo biloba Nitric oxide synthase, inducible target
Ginkgo biloba Cytochrome P450 1B1 enzyme
Ginkgo biloba Cytochrome P450 1A1 enzyme
Ginkgo biloba Cytochrome P450 1A2 enzyme
Viloxazine Sodium-dependent noradrenaline transporter target
Viloxazine Cytochrome P450 1A2 enzyme
Viloxazine Cytochrome P450 2D6 enzyme
Viloxazine UDP-glucuronosyltransferase 1-9 enzyme
Viloxazine UDP-glucuronosyltransferase 2B15 enzyme
Viloxazine Cytochrome P450 2B6 enzyme
Viloxazine Cytochrome P450 3A4 enzyme
Viloxazine Cytochrome P450 3A5 enzyme
Viloxazine Multidrug and toxin extrusion protein 1 transporter
Viloxazine 5-hydroxytryptamine receptor 2B target
Viloxazine 5-hydroxytryptamine receptor 2C target
Viloxazine Alpha-1B adrenergic receptor target
Viloxazine Beta-2 adrenergic receptor target
Viloxazine Amine oxidase [flavin-containing] A target
Viloxazine Amine oxidase [flavin-containing] B target
Viloxazine Histamine H1 receptor target
Viloxazine Histamine H2 receptor target
Viloxazine Muscarinic acetylcholine receptor M1 target
Viloxazine Muscarinic acetylcholine receptor M2 target
Viloxazine Muscarinic acetylcholine receptor M3 target
Viloxazine Muscarinic acetylcholine receptor M4 target