Advanced Renal Cell Carcinoma

Also known as:Advanced Renal Cell Cancer/Advanced Renal Cell Carcinoma (aRCC)/Advanced Renal Cell Carcinoma (RCC)/Adenocarcinoma of kidney/Renal cell cancer/Renal cell carcinoma stage unspecified/Grawitz tumor/Renal cell carcinoma NOS/Renal cell adenocarcinoma/Grawitz tumour/Renal cell carcinoma (disorder)/Renal cell carcinoma/Renal cell carcinoma (morphologic abnormality)/Carcinoma, Renal Cell/Clear cell carcinoma of kidney (disorder)

Drug Drug Name Drug Description
DB11945 Avelumab A monoclonal antibody used to treat metastatic merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma.
DB06626 Axitinib An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
DB08875 Cabozantinib A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
DB09078 Lenvatinib A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
DB09035 Nivolumab A PD-1 blocking antibody used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma.
DB06589 Pazopanib An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
DB09037 Pembrolizumab A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.
DB00398 Sorafenib A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma.
DB06287 Temsirolimus A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
DB11800 Tivozanib A kinase inhibitor to treat adult patients with renal cell carcinoma (RCC) who have failed prior systemic therapies or experienced relapsed disease.
Drug Drug Name Target Type
DB11945 Avelumab Programmed cell death 1 ligand 1 target
DB11945 Avelumab Programmed cell death protein 1 target
DB06626 Axitinib Vascular endothelial growth factor receptor 1 target
DB06626 Axitinib Vascular endothelial growth factor receptor 2 target
DB06626 Axitinib Vascular endothelial growth factor receptor 3 target
DB06626 Axitinib Cytochrome P450 3A4 enzyme
DB06626 Axitinib Cytochrome P450 3A5 enzyme
DB06626 Axitinib Cytochrome P450 1A2 enzyme
DB06626 Axitinib Cytochrome P450 2C19 enzyme
DB06626 Axitinib UDP-glucuronosyltransferase 1-1 enzyme
DB06626 Axitinib P-glycoprotein 1 transporter
DB06626 Axitinib Solute carrier organic anion transporter family member 1B1 transporter
DB08875 Cabozantinib Cytochrome P450 3A4 enzyme
DB08875 Cabozantinib Cytochrome P450 2C9 enzyme
DB08875 Cabozantinib Hepatocyte growth factor receptor target
DB08875 Cabozantinib Vascular endothelial growth factor receptor 2 target
DB08875 Cabozantinib Proto-oncogene tyrosine-protein kinase receptor Ret target
DB08875 Cabozantinib Cytochrome P450 2C8 enzyme
DB09078 Lenvatinib Vascular endothelial growth factor receptor 1 target
DB09078 Lenvatinib Vascular endothelial growth factor receptor 2 target
DB09078 Lenvatinib Vascular endothelial growth factor receptor 3 target
DB09078 Lenvatinib Fibroblast growth factor receptor 1 target
DB09078 Lenvatinib Fibroblast growth factor receptor 2 target
DB09078 Lenvatinib Fibroblast growth factor receptor 3 target
DB09078 Lenvatinib Fibroblast growth factor receptor 4 target
DB09078 Lenvatinib Platelet-derived growth factor receptor alpha target
DB09078 Lenvatinib Proto-oncogene tyrosine-protein kinase receptor Ret target
DB09078 Lenvatinib Mast/stem cell growth factor receptor Kit target
DB09078 Lenvatinib P-glycoprotein 1 transporter
DB09078 Lenvatinib ATP-binding cassette sub-family G member 2 transporter
DB09078 Lenvatinib Cytochrome P450 3A4 enzyme
DB09078 Lenvatinib Aldehyde oxidase enzyme
DB09078 Lenvatinib Cytochrome P450 2C8 enzyme
DB09078 Lenvatinib Cytochrome P450 2C9 enzyme
DB09078 Lenvatinib Cytochrome P450 1A2 enzyme
DB09078 Lenvatinib Cytochrome P450 2B6 enzyme
DB09078 Lenvatinib Cytochrome P450 2C19 enzyme
DB09078 Lenvatinib Solute carrier family 22 member 6 transporter
DB09078 Lenvatinib Solute carrier family 22 member 8 transporter
DB09078 Lenvatinib 溶质载体家庭22个成员2 transporter
DB09078 Lenvatinib Solute carrier organic anion transporter family member 1B1 transporter
DB09078 Lenvatinib Bile salt export pump transporter
DB09078 Lenvatinib Cytochrome P450 2D6 enzyme
DB09078 Lenvatinib Solute carrier organic anion transporter family member 1B3 transporter
DB09035 Nivolumab Programmed cell death protein 1 target
DB09035 Nivolumab Programmed cell death 1 ligand 1 target
DB06589 Pazopanib Vascular endothelial growth factor receptor 1 target
DB06589 Pazopanib Vascular endothelial growth factor receptor 2 target
DB06589 Pazopanib Vascular endothelial growth factor receptor 3 target
DB06589 Pazopanib Platelet-derived growth factor receptor alpha target
DB06589 Pazopanib Platelet-derived growth factor receptor beta target
DB06589 Pazopanib Mast/stem cell growth factor receptor Kit target
DB06589 Pazopanib Cytochrome P450 3A4 enzyme
DB06589 Pazopanib Cytochrome P450 2D6 enzyme
DB06589 Pazopanib Cytochrome P450 2C8 enzyme
DB06589 Pazopanib Cytochrome P450 1A2 enzyme
DB06589 Pazopanib P-glycoprotein 1 transporter
DB06589 Pazopanib ATP-binding cassette sub-family G member 2 transporter
DB06589 Pazopanib Solute carrier organic anion transporter family member 1B1 transporter
DB06589 Pazopanib UDP-glucuronosyltransferase 1-1 transporter
DB06589 Pazopanib Fibroblast growth factor receptor 3 target
DB06589 Pazopanib Tyrosine-protein kinase ITK/TSK target
DB06589 Pazopanib Fibroblast growth factor 1 target
DB06589 Pazopanib SH2B adapter protein 3 target
DB09037 Pembrolizumab Programmed cell death protein 1 target
DB09037 Pembrolizumab Programmed cell death 1 ligand 1 target
DB00398 Sorafenib Serine/threonine-protein kinase B-raf target
DB00398 Sorafenib Receptor-type tyrosine-protein kinase FLT3 target
DB00398 Sorafenib RAF proto-oncogene serine/threonine-protein kinase target
DB00398 Sorafenib Vascular endothelial growth factor receptor 3 target
DB00398 Sorafenib Platelet-derived growth factor receptor beta target
DB00398 Sorafenib Mast/stem cell growth factor receptor Kit target
DB00398 Sorafenib Vascular endothelial growth factor receptor 2 target
DB00398 Sorafenib Cytochrome P450 3A4 enzyme
DB00398 Sorafenib UDP-glucuronosyltransferase 1-9 enzyme
DB00398 Sorafenib Cytochrome P450 2B6 enzyme
DB00398 Sorafenib Cytochrome P450 2C8 enzyme
DB00398 Sorafenib Cytochrome P450 3A5 enzyme
DB00398 Sorafenib Cytochrome P450 3A7 enzyme
DB00398 Sorafenib Cytochrome P450 2C9 enzyme
DB00398 Sorafenib Multidrug resistance-associated protein 4 transporter
DB00398 Sorafenib P-glycoprotein 1 transporter
DB00398 Sorafenib 运河icular multispecific organic anion transporter 1 transporter
DB00398 Sorafenib ATP-binding cassette sub-family G member 2 transporter
DB00398 Sorafenib Cytochrome P450 1A2 enzyme
DB00398 Sorafenib Cytochrome P450 2C19 enzyme
DB00398 Sorafenib Cytochrome P450 2D6 enzyme
DB00398 Sorafenib UDP-glucuronosyltransferase 1-1 enzyme
DB00398 Sorafenib RalA-binding protein 1 transporter
DB00398 Sorafenib Fibroblast growth factor receptor 1 target
DB00398 Sorafenib Proto-oncogene tyrosine-protein kinase receptor Ret target
DB00398 Sorafenib Vascular endothelial growth factor receptor 1 target
DB00398 Sorafenib Solute carrier organic anion transporter family member 1B1 transporter
DB06287 Temsirolimus Serine/threonine-protein kinase mTOR target
DB06287 Temsirolimus Cytochrome P450 3A4 enzyme
DB06287 Temsirolimus Cytochrome P450 3A5 enzyme
DB06287 Temsirolimus Cytochrome P450 3A7 enzyme
DB06287 Temsirolimus Cytochrome P450 2D6 enzyme
DB06287 Temsirolimus P-glycoprotein 1 transporter
DB11800 Tivozanib Cytochrome P450 3A4 enzyme
DB11800 Tivozanib Serum albumin carrier
DB11800 Tivozanib Vascular endothelial growth factor receptor 1 target
DB11800 Tivozanib Vascular endothelial growth factor receptor 2 target
DB11800 Tivozanib Vascular endothelial growth factor receptor 3 target
DB11800 Tivozanib Mast/stem cell growth factor receptor Kit target
DB11800 Tivozanib Platelet-derived growth factor receptor beta target
DB11800 Tivozanib P-glycoprotein 1 transporter
DB11800 Tivozanib ATP-binding cassette sub-family G member 2 transporter
DB11800 Tivozanib Receptor-type tyrosine-protein kinase FLT3 target
DB11800 Tivozanib Platelet-derived growth factor receptor alpha target
DB11800 Tivozanib Protein-tyrosine kinase 6 target
DB11800 Tivozanib Angiopoietin-1 receptor target
DB11800 Tivozanib Fibroblast growth factor receptor 1 target
DB11800 Tivozanib Hepatocyte growth factor receptor target
Drug Drug Name Phase Status Count
DB00062 Albumin human 1 Recruiting 1
DB11595 Atezolizumab 1 Recruiting 1
DB06626 Axitinib 1 Recruiting 1
DB08875 Cabozantinib 1 Recruiting 3
DB06091 Evofosfamide 1 Unknown Status 1
DB06186 Ipilimumab 1 Active Not Recruiting 1
DB09078 Lenvatinib 1 Recruiting 1
DB09035 Nivolumab 1 Active Not Recruiting 1
DB09035 Nivolumab 1 Recruiting 2
DB01229 Paclitaxel 1 Recruiting 1
DB11595 Atezolizumab 1 / 2 Recruiting 1
DB11945 Avelumab 1 / 2 Recruiting 1
DB00531 Cyclophosphamide 1 / 2 Recruiting 1
DB11714 Durvalumab 1 / 2 Recruiting 1
DB01073 Fludarabine 1 / 2 Recruiting 1
DB17475 不完全弗氏佐剂 1 / 2 Unknown Status 1
DB05258 Interferon alfa 1 / 2 Completed 1
DB09078 Lenvatinib 1 / 2 Not Yet Recruiting 1
DB15721 Natural Killer Cell 1 / 2 Recruiting 1
DB09035 Nivolumab 1 / 2 Recruiting 1
DB06589 Pazopanib 1 / 2 Completed 1
DB09037 Pembrolizumab 1 / 2 Recruiting 1
DB05992 Plinabulin 1 / 2 Recruiting 1
DB11595 Atezolizumab 2 Recruiting 1
DB06626 Axitinib 2 Terminated 1
DB00112 Bevacizumab 2 Completed 1
DB08875 Cabozantinib 2 Completed 2
DB08875 Cabozantinib 2 Recruiting 1
DB14988 Dalantercept 2 Terminated 1
DB01070 Dihydrotachysterol 2 Completed 1
DB00530 Erlotinib 2 Recruiting 1
DB01590 Everolimus 2 Recruiting 1
DB09398 Fluoride ion F-18 2 Recruiting 1
DB05304 Girentuximab 2 Recruiting 1
DB06186 Ipilimumab 2 Active Not Recruiting 1
DB06186 Ipilimumab 2 Recruiting 1
DB09078 Lenvatinib 2 Recruiting 1
DB06080 Linifanib 2 Completed 1
DB13982 Lutetium Lu-177 2 Recruiting 1
DB09035 Nivolumab 2 Active Not Recruiting 1
DB09035 Nivolumab 2 Recruiting 2
DB01269 Panitumumab 2 Completed 2
DB06589 Pazopanib 2 Completed 1
DB11972 Rilotumumab 2 Completed 1
DB00398 Sorafenib 2 Completed 2
DB01268 Sunitinib 2 Completed 2
DB15232 Telaglenastat 2 Completed 1
DB06287 Temsirolimus 2 Completed 1
DB12056 Trebananib 2 Completed 3
DB06626 Axitinib 2 / 3 Not Yet Recruiting 1
DB01590 Everolimus 2 / 3 Not Yet Recruiting 1
DB11679 Fruquintinib 2 / 3 Not Yet Recruiting 1
DB15765 Sintilimab 2 / 3 Not Yet Recruiting 1
DB06186 Ipilimumab 3 Active Not Recruiting 1
DB09035 Nivolumab 3 Active Not Recruiting 1
DB00398 Sorafenib 3 Completed 2
DB01268 Sunitinib 3 Active Not Recruiting 1
DB01268 Sunitinib 3 Terminated 1
DB11800 Tivozanib 3 Completed 2
DB11945 Avelumab Not Available Recruiting 1
DB06626 Axitinib Not Available Completed 1
DB06626 Axitinib Not Available Recruiting 1
DB00398 Sorafenib Not Available Completed 2
DB01268 Sunitinib Not Available Completed 1
DB06287 Temsirolimus Not Available Completed 1