Propanolamines

Name
Propanolamines
Accession Number
DBCAT000483
Description

AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.

Drugs
Drug Drug Description
Betaxolol A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Metoprolol A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
Timolol A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
Bisoprolol 一个beta 1用于防止肾上腺素能阻滞剂myocardial infarction and heart failure and to treat mild to moderate hypertension.
Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
Ritodrine An adrenergic beta agonist used to treat premature labor.
Pindolol A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Nadolol A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension.
Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion.
Isoxsuprine A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
Suloctidil Not Annotated
Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
Methoxamine An alpha adrenergic agonist used to treat hypotension.
Alprenolol For the treatment of hypertension, angina, and arrhythmia
Histidinol Not Available
Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
Oxyfedrine Not Annotated
Carteolol A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
Metaraminol For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage
Tolterodine A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
Levobunolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Metipranolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Practolol Used in the emergency treatment of cardiac arrhythmias.
Penbutolol A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents.
Cathine Used to decrease appetite.
Oxprenolol A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety.
Dexpropranolol Not Available
Celiprolol A beta-blocker for the management of hypertension and angina pectoris.
Bopindolol For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
Bupranolol Used to manage hypertension and tachycardia. Also used to treat glaucoma.
DL-Methylephedrine Used as an antitussive and decongestant .
Etafedrine A beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa.
Oxilofrine An amphetamine used to treat a cough associated with inflamed mucosa.
Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Mepindolol Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker.
Prenalterol Not Annotated
Xamoterol Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but...
Drugs & Drug Targets
Drug Target Type
Betaxolol Beta-1 adrenergic receptor target
Betaxolol Beta-2 adrenergic receptor target
Betaxolol Cytochrome P450 1A2 enzyme
Betaxolol Cytochrome P450 2D6 enzyme
Metoprolol Beta-1 adrenergic receptor target
Metoprolol Cytochrome P450 2D6 enzyme
Metoprolol Beta-2 adrenergic receptor target
Metoprolol 溶质载体家庭22个成员2 transporter
Metoprolol Serum albumin carrier
Metoprolol Cytochrome P450 3A4 enzyme
Metoprolol Beta adrenergic receptor target
Timolol Beta-1 adrenergic receptor target
Timolol Beta-2 adrenergic receptor target
Timolol Cytochrome P450 2D6 enzyme
Timolol P-glycoprotein 1 transporter
Timolol Cytochrome P450 2C19 enzyme
Timolol Lysozyme target
Phenylpropanolamine Amine oxidase [flavin-containing] A enzyme
Phenylpropanolamine Dopamine D1 receptor target
Phenylpropanolamine Beta-1 adrenergic receptor target
Phenylpropanolamine Beta-2 adrenergic receptor target
Phenylpropanolamine Alpha-2 adrenergic receptors target
Propranolol Beta-1 adrenergic receptor target
Propranolol Beta-2 adrenergic receptor target
Propranolol Beta-3 adrenergic receptor target
Propranolol 5-hydroxytryptamine receptor 1A target
Propranolol 5-hydroxytryptamine receptor 1B target
Propranolol Cytochrome P450 1A2 enzyme
Propranolol Cytochrome P450 2D6 enzyme
Propranolol Alpha-1-acid glycoprotein 1 carrier
Propranolol Cytochrome P450 2C19 enzyme
Propranolol Cytochrome P450 3A4 enzyme
Propranolol Cytochrome P450 3A5 enzyme
Propranolol Cytochrome P450 3A7 enzyme
Propranolol 溶质载体家庭22个成员2 transporter
Propranolol P-glycoprotein 1 transporter
Propranolol Cytochrome P450 1A1 enzyme
Propranolol Amine oxidase [flavin-containing] A enzyme
Propranolol Serum albumin carrier
Bisoprolol Beta-1 adrenergic receptor target
Bisoprolol Beta-2 adrenergic receptor target
Bisoprolol Cytochrome P450 3A4 enzyme
Bisoprolol P-glycoprotein 1 transporter
Pseudoephedrine Alpha-1A adrenergic receptor target
Pseudoephedrine Alpha-2A adrenergic receptor target
Pseudoephedrine Beta-2 adrenergic receptor target
Pseudoephedrine Amine oxidase [flavin-containing] A enzyme
Pseudoephedrine Beta-1 adrenergic receptor target
Pseudoephedrine Sodium-dependent dopamine transporter target
Pseudoephedrine Sodium-dependent noradrenaline transporter target
Pseudoephedrine Sodium-dependent serotonin transporter target
Pseudoephedrine Nuclear factor of activated T-cells, cytoplasmic 1 target
Pseudoephedrine Tumor necrosis factor target
Pseudoephedrine Nuclear factor NF-kappa-B p105 subunit target
Pseudoephedrine activator protein 1 target
Pseudoephedrine Interleukin-2 target
Pseudoephedrine Serum albumin carrier
Pseudoephedrine Sodium-dependent noradrenaline transporter transporter
Pseudoephedrine Sodium-dependent dopamine transporter transporter
Pseudoephedrine Sodium-dependent serotonin transporter transporter
Ritodrine Beta-2 adrenergic receptor target
Ritodrine 6-phosphogluconate dehydrogenase, decarboxylating enzyme
Ritodrine Sulfotransferase 1A1 enzyme
Ritodrine Sulfotransferase 1A3/1A4 enzyme
Ritodrine Beta adrenergic receptor target
Ritodrine ATP-sensitive potassium channel target
Ritodrine Calcium transporting ATPases target
Ritodrine Calcium-activated potassium channel target
Ritodrine Myosin light chain kinase, smooth muscle target
Ritodrine Sulfotransferase 1C4 target
Ritodrine Sulfotransferase enzyme
Ritodrine Sulfotransferase 1C4 enzyme
Pindolol Beta-1 adrenergic receptor target
Pindolol Beta-2 adrenergic receptor target
Pindolol 5-hydroxytryptamine receptor 1A target
Pindolol 5-hydroxytryptamine receptor 1B target
Pindolol Cytochrome P450 2D6 enzyme
Pindolol Beta-3 adrenergic receptor target
Pindolol UDP-glucuronosyltransferases (UGTs) enzyme
Pindolol Sulfotransferase enzyme
Pindolol 溶质载体家庭22个成员2 transporter
Pindolol alpha1-acid glycoprotein carrier
Nadolol Beta-1 adrenergic receptor target
Nadolol Beta-2 adrenergic receptor target
Nadolol P-glycoprotein 1 transporter
Nadolol POU domain, class 2, transcription factor 1 transporter
Nadolol POU domain, class 2, transcription factor 2 transporter
Nadolol Multidrug and toxin extrusion protein 1 transporter
Nadolol Multidrug and toxin extrusion protein 2 transporter
Nadolol alpha1-acid glycoprotein carrier
Ephedrine Alpha-1A adrenergic receptor target
Ephedrine Sodium-dependent noradrenaline transporter target
Ephedrine Cholinesterase enzyme
Ephedrine Serum albumin carrier
Ephedrine Beta-1 adrenergic receptor target
Ephedrine Beta-2 adrenergic receptor target
Ephedrine Synaptic vesicular amine transporter transporter
Ephedrine Acetylcholinesterase enzyme
Carvedilol Alpha-1A adrenergic receptor target
Carvedilol Beta-1 adrenergic receptor target
Carvedilol NADH dehydrogenase [ubiquinone] 1 subunit C2 target
Carvedilol Beta-2 adrenergic receptor target
Carvedilol Vascular endothelial growth factor A target
Carvedilol Natriuretic peptides B target
Carvedilol Gap junction alpha-1 protein target
Carvedilol Potassium voltage-gated channel subfamily H member 2 target
Carvedilol Vascular cell adhesion protein 1 target
Carvedilol Cytochrome P450 2C9 enzyme
Carvedilol Cytochrome P450 2D6 enzyme
Carvedilol Xanthine dehydrogenase/oxidase enzyme
Carvedilol P-glycoprotein 1 transporter
Carvedilol Cytochrome P450 1A2 enzyme
Carvedilol Cytochrome P450 3A4 enzyme
Carvedilol Cytochrome P450 1A1 enzyme
Carvedilol Cytochrome P450 2E1 enzyme
Carvedilol Alpha-1D adrenergic receptor target
Carvedilol Alpha-1B adrenergic receptor target
Carvedilol Alpha-2C adrenergic receptor target
Carvedilol Alpha-2B adrenergic receptor target
Carvedilol Alpha-2A adrenergic receptor target
Carvedilol E-selectin target
Carvedilol Hypoxia-inducible factor 1-alpha target
Carvedilol Inward rectifier potassium channel 4 target
Carvedilol UDP-glucuronosyltransferase 1-1 enzyme
Carvedilol Serum albumin carrier
Carvedilol UDP-glucuronosyltransferase 2B4 enzyme
Carvedilol UDP-glucuronosyltransferase 2B7 enzyme
Carvedilol Inward rectifier potassium channel 2 target
Carvedilol Alpha-1 adrenergic receptors target
Methoxamine Alpha-1A adrenergic receptor target
Methoxamine Alpha-1B adrenergic receptor target
Methoxamine Alpha-1D adrenergic receptor target
Alprenolol Beta-1 adrenergic receptor target
Alprenolol Beta-2 adrenergic receptor target
Alprenolol 5-hydroxytryptamine receptor 1A target
Alprenolol Cytochrome P450 2D6 enzyme
Alprenolol Beta-3 adrenergic receptor target
Histidinol Histidinol dehydrogenase target
Histidinol Histidine--tRNA ligase target
Nylidrin Catechol O-methyltransferase enzyme
Nylidrin Voltage-dependent T-type calcium channel subunit alpha-1I target
Nylidrin Interferon alpha/beta receptor 2 target
Nylidrin Cytochrome P450 3A4 enzyme
Carteolol Beta-2 adrenergic receptor target
Carteolol Beta-1 adrenergic receptor target
Carteolol Cytochrome P450 2D6 enzyme
Metaraminol Alpha-1A adrenergic receptor target
Tolterodine Muscarinic acetylcholine receptor M1 target
Tolterodine Muscarinic acetylcholine receptor M2 target
Tolterodine Muscarinic acetylcholine receptor M3 target
Tolterodine Cytochrome P450 2D6 enzyme
Tolterodine Cytochrome P450 3A4 enzyme
Tolterodine Cytochrome P450 2C9 enzyme
Tolterodine Cytochrome P450 2C19 enzyme
Tolterodine Muscarinic acetylcholine receptor M4 target
Tolterodine Muscarinic acetylcholine receptor M5 target
Acebutolol Beta-1 adrenergic receptor target
Acebutolol Cytochrome P450 2D6 enzyme
Acebutolol Beta-2 adrenergic receptor target
Acebutolol P-glycoprotein 1 transporter
Levobunolol Beta-1 adrenergic receptor target
Levobunolol Beta-2 adrenergic receptor target
Levobunolol Cytochrome P450 2D6 enzyme
Metipranolol Beta-1 adrenergic receptor target
Metipranolol Beta-2 adrenergic receptor target
Metipranolol Cytochrome P450 2D6 enzyme
Practolol Beta-1 adrenergic receptor target
Practolol Cytochrome P450 2D6 enzyme
Penbutolol Alpha-1-acid glycoprotein 1 carrier
Penbutolol Beta-1 adrenergic receptor target
Penbutolol Beta-2 adrenergic receptor target
Penbutolol 5-hydroxytryptamine receptor 1A target
Penbutolol 5-hydroxytryptamine receptor 1B target
Penbutolol Cytochrome P450 2D6 enzyme
Oxprenolol Beta-1 adrenergic receptor target
Oxprenolol Beta-2 adrenergic receptor target
Oxprenolol 溶质载体家庭22个成员2 transporter
Oxprenolol Cytochrome P450 2D6 enzyme
Oxprenolol Beta-3 adrenergic receptor target
Celiprolol Beta-1 adrenergic receptor target
Celiprolol Beta-2 adrenergic receptor target
Celiprolol Beta-3 adrenergic receptor target
Celiprolol Alpha-2A adrenergic receptor target
Celiprolol Alpha-2B adrenergic receptor target
Celiprolol Alpha-2C adrenergic receptor target
Celiprolol Cytochrome P450 2D6 enzyme
Bopindolol Beta-1 adrenergic receptor target
Bopindolol Beta-2 adrenergic receptor target
Bopindolol 5-hydroxytryptamine receptor 1A target
Bopindolol 5-hydroxytryptamine receptor 1B target
Bopindolol Beta-3 adrenergic receptor target
Bopindolol Cytochrome P450 2D6 enzyme
Bupranolol Beta-1 adrenergic receptor target
Bupranolol Beta-2 adrenergic receptor target
Bupranolol Beta-3 adrenergic receptor target
Bupranolol Cytochrome P450 2D6 enzyme
DL-Methylephedrine Beta-1 adrenergic receptor target
DL-Methylephedrine Alpha-2A adrenergic receptor target
DL-Methylephedrine Alpha adrenergic receptor target
DL-Methylephedrine Beta adrenergic receptor target
Etafedrine Beta-2 adrenergic receptor target
Mepindolol Cytochrome P450 2D6 enzyme
Xamoterol Beta-1 adrenergic receptor target