Alcohol Dependency

Also known as:Alcohol Addiction/Alcoholics/Alcoholic/Alcoholism/Addiction, Alcohol/Alcohol Dependence/Alcohol-dependence/Alcoholdependence/Alcohol Dependent/Persistent alcohol abuse (disorder)/Unspecified chronic alcoholism (disorder)/Alcohol abuse chronic/酒精dependence syndrome (& [dipsomania])/酒精dependence (disorder)/Dipsomania/慢性艾可holism [Ambiguous]/慢性艾可holism (& [dipsomania])/Dipsomania (finding)/[X] (Mental and behavioural disorders due to use of alcohol: dependence syndrome) or (chronic alcoholism [& (addiction) or (dipsomania)])/[X]Mental and behavioral disorders due to use of alcohol: dependence syndrome (disorder)/慢性艾可holism/慢性艾可holism NOS (disorder)/Alcoholism (disorder)/(Alcohol dependence syndrome [including alcoholism]) or (alcohol problem drinking)/Alcohol abuse, continuous drinking behaviour/Alcohol abuse, continuous drinking behavior/酒精dependence syndrome/酒精dependence syndrome NOS (disorder)/Problem drinker (life style)

Drug Drug Name Drug Description
DB00659 Acamprosate A medication used to maintain alcohol abstinence in patients with alcohol dependence.
DB00181 Baclofen A GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.
DB01142 Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
DB00472 Fluoxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
DB06230 Nalmefene An opioid antagonist used to reduce alcohol consumption in adults with alcohol dependence and treat and prevent opioid overdose.
DB00704 Naltrexone A narcotic antagonist used in opioid overdose.
DB09210 Piracetam A nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
DB13025 Tiapride A dopamine D2 and D3 receptor antagonist indicated in the treatment of chorea in Huntington's disease, as well as agitation and anxiety in the elderly or with acute or chronic alcoholism.
DB00273 Topiramate An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
DB00656 Trazodone A serotonin uptake inhibitor used to treat major depressive disorder.
Drug Drug Name Target Type
DB00659 Acamprosate Metabotropic glutamate receptor 5 target
DB00659 Acamprosate Solute carrier family 22 member 6 transporter
DB00659 Acamprosate Glutamate (NMDA) receptor target
DB00659 Acamprosate Gamma-aminobutyric acid type B receptor subunit 1 target
DB00181 Baclofen Gamma-aminobutyric acid type B receptor subunit 1 target
DB00181 Baclofen Gamma-aminobutyric acid type B receptor subunit 2 target
DB00181 Baclofen C-X-C chemokine receptor type 4 target
DB01142 Doxepin Sodium-dependent serotonin transporter target
DB01142 Doxepin Sodium-dependent noradrenaline transporter target
DB01142 Doxepin Histamine H1 receptor target
DB01142 Doxepin Histamine H2 receptor target
DB01142 Doxepin Cytochrome P450 2D6 enzyme
DB01142 Doxepin Muscarinic acetylcholine receptor M1 target
DB01142 Doxepin Muscarinic acetylcholine receptor M2 target
DB01142 Doxepin Muscarinic acetylcholine receptor M3 target
DB01142 Doxepin Muscarinic acetylcholine receptor M4 target
DB01142 Doxepin Muscarinic acetylcholine receptor M5 target
DB01142 Doxepin Alpha-1A adrenergic receptor target
DB01142 Doxepin 5-hydroxytryptamine receptor 1A target
DB01142 Doxepin 5-hydroxytryptamine receptor 2A target
DB01142 Doxepin Cytochrome P450 2C19 enzyme
DB01142 Doxepin Cytochrome P450 2C9 enzyme
DB01142 Doxepin Cytochrome P450 1A2 enzyme
DB01142 Doxepin P-glycoprotein 1 transporter
DB01142 Doxepin 5-hydroxytryptamine receptor 2B target
DB01142 Doxepin 5-hydroxytryptamine receptor 2C target
DB01142 Doxepin Alpha-1B adrenergic receptor target
DB01142 Doxepin Alpha-1D adrenergic receptor target
DB01142 Doxepin Cytochrome P450 3A4 enzyme
DB01142 Doxepin 5-hydroxytryptamine receptor 6 target
DB01142 Doxepin Histamine H4 receptor target
DB01142 Doxepin Potassium voltage-gated channel subfamily H member 2 target
DB01142 Doxepin Serum albumin carrier
DB01142 Doxepin Alpha-1-acid glycoprotein 1 carrier
DB00472 Fluoxetine Sodium-dependent serotonin transporter target
DB00472 Fluoxetine Cytochrome P450 2C9 enzyme
DB00472 Fluoxetine Cytochrome P450 2D6 enzyme
DB00472 Fluoxetine CYP2B protein enzyme
DB00472 Fluoxetine Cytochrome P450 1A2 enzyme
DB00472 Fluoxetine Cytochrome P450 3A4 enzyme
DB00472 Fluoxetine Cytochrome P450 2C19 enzyme
DB00472 Fluoxetine P-glycoprotein 1 transporter
DB00472 Fluoxetine Cytochrome P450 2B6 enzyme
DB00472 Fluoxetine Cytochrome P450 3A5 enzyme
DB00472 Fluoxetine Serum albumin carrier
DB00472 Fluoxetine Alpha-1-acid glycoprotein 1 carrier
DB00472 Fluoxetine Potassium voltage-gated channel subfamily H member 2 target
DB00472 Fluoxetine 5-hydroxytryptamine receptor 2C target
DB00472 Fluoxetine Cyclin-dependent kinases regulatory subunit 1 target
DB00472 Fluoxetine Neuronal acetylcholine receptor subunit alpha-2 target
DB00472 Fluoxetine Neuronal acetylcholine receptor subunit alpha-3 target
DB00472 Fluoxetine Neuronal acetylcholine receptor subunit beta-4 target
DB06230 Nalmefene Mu-type opioid receptor target
DB06230 Nalmefene Kappa-type opioid receptor target
DB06230 Nalmefene Delta-type opioid receptor target
DB06230 Nalmefene UDP-glucuronosyltransferase 2B7 enzyme
DB06230 Nalmefene UDP-glucuronosyltransferase 1-3 enzyme
DB06230 Nalmefene UDP-glucuronosyltransferase 1-8 enzyme
DB06230 Nalmefene Cytochrome P450 3A4 enzyme
DB06230 Nalmefene Cytochrome P450 3A5 enzyme
DB00704 Naltrexone Mu-type opioid receptor target
DB00704 Naltrexone Kappa-type opioid receptor target
DB00704 Naltrexone Delta-type opioid receptor target
DB00704 Naltrexone UDP-glucuronosyltransferase 1-1 enzyme
DB00704 Naltrexone Sigma non-opioid intracellular receptor 1 target
DB13025 Tiapride Dopamine D2 receptor target
DB13025 Tiapride Dopamine D3 receptor target
DB13025 Tiapride Serotonin Receptors target
DB13025 Tiapride Alpha-1 adrenergic receptors target
DB13025 Tiapride Alpha-2 adrenergic receptors target
DB00273 Topiramate Gamma-aminobutyric acid receptor subunit alpha-1 target
DB00273 Topiramate Voltage-gated sodium channel alpha subunit target
DB00273 Topiramate Carbonic anhydrase 2 target
DB00273 Topiramate Carbonic anhydrase 4 target
DB00273 Topiramate Kainate receptors target
DB00273 Topiramate Cytochrome P450 2C19 enzyme
DB00273 Topiramate Cytochrome P450 3A4 enzyme
DB00273 Topiramate Carbonic anhydrase 1 target
DB00273 Topiramate Carbonic anhydrase 3 target
DB00273 Topiramate Voltage gated L-type calcium channel target
DB00273 Topiramate Voltage-dependent R-type calcium channel target
DB00273 Topiramate Serum albumin carrier
DB00273 Topiramate P-glycoprotein 1 transporter
DB00273 Topiramate 5'-AMP-activated protein kinase transporter
DB00656 Trazodone 5-hydroxytryptamine receptor 2A target
DB00656 Trazodone Sodium-dependent serotonin transporter target
DB00656 Trazodone Alpha-1A adrenergic receptor target
DB00656 Trazodone Alpha-2A adrenergic receptor target
DB00656 Trazodone Histamine H1 receptor target
DB00656 Trazodone 5-hydroxytryptamine receptor 1A target
DB00656 Trazodone Cytochrome P450 2D6 enzyme
DB00656 Trazodone Cytochrome P450 3A4 enzyme
DB00656 Trazodone 5-hydroxytryptamine receptor 2C target
DB00656 Trazodone Cytochrome P450 3A5 enzyme
DB00656 Trazodone Cytochrome P450 3A7 enzyme
DB00656 Trazodone P-glycoprotein 1 transporter
DB00656 Trazodone 5-hydroxytryptamine receptor 1C target
Drug Drug Name Phase Status Count
DB09061 Cannabidiol 0 Unknown Status 1
DB00151 Cysteine 0 Unknown Status 1
DB00898 Ethanol 0 Active Not Recruiting 1
DB01276 Exenatide 0 Unknown Status 1
DB11895 Lenomorelin 0 Unknown Status 1
DB06230 Nalmefene 0 Terminated 1
DB00704 Naltrexone 0 Completed 1
DB00107 Oxytocin 0 Completed 1
DB00273 Topiramate 0 Unknown Status 1
DB00181 Baclofen 1 Completed 1
DB11105 Benzalkonium 1 Completed 1
DB06770 Benzyl alcohol 1 Completed 1
DB00215 Citalopram 1 Completed 1
DB00470 Dronabinol 1 Completed 1
DB00898 Ethanol 1 Completed 1
DB00898 Ethanol 1 Terminated 1
DB12886 GSK-1521498 1 Completed 2
DB01018 Guanfacine 1 Completed 1
DB01221 Ketamine 1 Completed 1
DB12341 LY-2456302 1 Completed 1
DB01017 Minocycline 1 Completed 1
DB01017 Minocycline 1 Recruiting 1
DB06230 Nalmefene 1 Completed 2
DB00704 Naltrexone 1 Completed 3
DB00704 Naltrexone 1 没有招聘 1
DB00704 Naltrexone 1 Terminated 1
DB05423 ORG-34517 1 Completed 1
DB00904 Ondansetron 1 Completed 1
DB00107 Oxytocin 1 Completed 1
DB00107 Oxytocin 1 Withdrawn 1
DB14870 PF-5190457 1 Completed 1
DB06663 Pasireotide 1 Completed 1
DB12543 Samidorphan 1 Completed 1
DB11805 Saracatinib 1 Completed 1
DB01104 Sertraline 1 Completed 1
DB00877 Sirolimus 1 Completed 1
DB00906 Tiagabine 1 Completed 1
DB00273 Topiramate 1 Completed 1
DB00659 Acamprosate 1 / 2 Completed 1
DB06151 Acetylcysteine 1 / 2 Completed 1
DB12338 Carisbamate 1 / 2 Completed 1
DB00704 Naltrexone 1 / 2 Completed 2
DB08883 Perampanel 1 / 2 Completed 1
DB00457 Prazosin 1 / 2 Completed 2
DB00313 Valproic acid 1 / 2 Completed 1
DB00659 Acamprosate 2 Completed 4
DB00659 Acamprosate 2 Unknown Status 1
DB06151 Acetylcysteine 2 Completed 1
DB00714 Apomorphine 2 Unknown Status 1
DB00673 Aprepitant 2 Completed 3
DB01238 Aripiprazole 2 Completed 2
DB16048 BTRX-246040 2 Completed 1
DB00181 Baclofen 2 Completed 3
DB00181 Baclofen 2 Terminated 1
DB12299 Bavisant 2 Withdrawn 1
DB01156 Bupropion 2 Completed 1
DB01156 Bupropion 2 Recruiting 1
DB12196 CP-866087 2 Completed 1
DB00215 Citalopram 2 Completed 1
DB00434 Cyproheptadine 2 Completed 1
DB01151 Desipramine 2 Completed 1
DB01075 Diphenhydramine 2 Completed 1
DB00822 Disulfiram 2 Completed 1
DB00590 Doxazosin 2 Completed 2
DB00476 Duloxetine 2 Completed 1
DB00898 Ethanol 2 Completed 1
DB00898 Ethanol 2 Terminated 1
DB01276 Exenatide 2 Completed 1
DB01039 Fenofibrate 2 Completed 1
DB13873 Fenofibric acid 2 Completed 1
DB00472 Fluoxetine 2 Completed 1
DB00996 Gabapentin 2 Completed 2
DB00145 Glycine 2 Completed 1
DB05266 Ibudilast 2 Recruiting 1
DB01221 Ketamine 2 Recruiting 1
DB04465 Lactose 2 Completed 1
DB11895 Lenomorelin 2 Completed 1
DB01202 Levetiracetam 2 Completed 2
DB01202 Levetiracetam 2 Terminated 1
DB00186 Lorazepam 2 Completed 1
DB00657 Mecamylamine 2 Completed 1
DB16554 Metadoxine 2 Completed 1
DB01577 Metamfetamine 2 没有招聘 1
DB00834 Mifepristone 2 Completed 2
DB00370 Mirtazapine 2 Completed 2
DB00745 Modafinil 2 Completed 1
DB00704 Naltrexone 2 Completed 14
DB12220 ORG-25935 2 Terminated 1
DB00334 奥氮平 2 Completed 1
DB00904 Ondansetron 2 Completed 5
DB00904 Ondansetron 2 Terminated 1
DB00904 Ondansetron 2 Unknown Status 1
DB12585 Ondelopran 2 Completed 1
DB00107 Oxytocin 2 Completed 2
DB14870 PF-5190457 2 Terminated 1
DB12572 Pexacerfont 2 Completed 1
DB01132 Pioglitazone 2 Terminated 2
DB00457 Prazosin 2 Completed 1
DB00230 Pregabalin 2 Completed 1
DB00571 Propranolol 2 Completed 1
DB11664 Psilocybin 2 Completed 1
DB11664 Psilocybin 2 Unknown Status 1
DB01224 Quetiapine 2 Completed 4
DB00734 Risperidone 2 Completed 1
DB12543 Samidorphan 2 Completed 1
DB12973 Serlopitant 2 Terminated 1
DB01104 Sertraline 2 Completed 4
DB01104 Sertraline 2 Terminated 1
DB09153 Sodium chloride 2 Completed 1
DB00273 Topiramate 2 Completed 6
DB00273 Topiramate 2 Terminated 2
DB00273 Topiramate 2 Unknown Status 1
DB12580 Tradipitant 2 Completed 2
DB00656 Trazodone 2 Completed 1
DB00313 Valproic acid 2 Completed 1
DB01273 Varenicline 2 Completed 5
DB01273 Varenicline 2 Recruiting 1
DB01273 Varenicline 2 Unknown Status 1
DB12512 Verucerfont 2 Completed 1
DB01080 Vigabatrin 2 Terminated 1
DB09068 Vortioxetine 2 Unknown Status 1
DB01392 Yohimbine 2 Completed 1
DB00909 Zonisamide 2 Completed 2
DB00909 Zonisamide 2 Terminated 1
DB12110 m-Chlorophenylpiperazine 2 Completed 1
DB01238 Aripiprazole 2 / 3 Completed 1
DB00181 Baclofen 2 / 3 Completed 3
DB01205 Flumazenil 2 / 3 Completed 1
DB00996 Gabapentin 2 / 3 Completed 2
DB00704 Naltrexone 2 / 3 Completed 1
DB00704 Naltrexone 2 / 3 Recruiting 1
DB00904 Ondansetron 2 / 3 Withdrawn 1
DB00107 Oxytocin 2 / 3 Recruiting 1
DB00396 Progesterone 2 / 3 Completed 1
DB00273 Topiramate 2 / 3 Active Not Recruiting 1
DB00273 Topiramate 2 / 3 Completed 2
DB00313 Valproic acid 2 / 3 Completed 1
DB01273 Varenicline 2 / 3 Completed 1
DB00659 Acamprosate 3 Completed 2
DB00659 Acamprosate 3 Recruiting 1
DB01238 Aripiprazole 3 Completed 1
DB01238 Aripiprazole 3 Recruiting 1
DB00181 Baclofen 3 Completed 3
DB01373 Calcium 3 Recruiting 1
DB06724 Calcium carbonate 3 Recruiting 1
DB00475 Chlordiazepoxide 3 Completed 1
DB01151 Desipramine 3 Completed 1
DB00996 Gabapentin 3 Completed 1
DB00555 Lamotrigine 3 Withdrawn 1
DB01202 Levetiracetam 3 Completed 1
DB14509 Lithium carbonate 3 Completed 1
DB00657 Mecamylamine 3 Completed 1
DB06230 Nalmefene 3 Completed 5
DB06230 Nalmefene 3 Unknown Status 1
DB01183 Naloxone 3 Completed 1
DB00704 Naltrexone 3 Completed 16
DB00704 Naltrexone 3 Terminated 1
DB00704 Naltrexone 3 Unknown Status 2
DB00334 奥氮平 3 Completed 1
DB00904 Ondansetron 3 Completed 2
DB12585 Ondelopran 3 Completed 1
DB00107 Oxytocin 3 Completed 2
DB00715 Paroxetine 3 Completed 1
DB00457 Prazosin 3 Completed 1
DB01224 Quetiapine 3 Completed 3
DB00273 Topiramate 3 Unknown Status 2
DB00273 Topiramate 3 Withdrawn 2
DB00313 Valproic acid 3 Completed 2
DB01273 Varenicline 3 Terminated 1
DB00909 Zonisamide 3 Completed 1
DB00659 Acamprosate 4 Completed 8
DB00659 Acamprosate 4 Terminated 1
DB00659 Acamprosate 4 Unknown Status 2
DB06151 Acetylcysteine 4 Unknown Status 1
DB01238 Aripiprazole 4 Completed 1
DB00181 Baclofen 4 Completed 1
DB11748 Benfotiamine 4 Completed 1
DB01156 Bupropion 4 Completed 1
DB01156 Bupropion 4 Terminated 1
DB03568 Butyric Acid 4 Completed 2
DB00564 Carbamazepine 4 Completed 1
DB00122 Choline 4 Completed 1
DB12153 Citicoline 4 Completed 1
DB00907 Cocaine 4 Unknown Status 1
DB00822 Disulfiram 4 Completed 2
DB00822 Disulfiram 4 Unknown Status 1
DB01126 Dutasteride 4 Completed 2
DB01175 Escitalopram 4 Completed 2
DB00898 Ethanol 4 Completed 1
DB00898 Ethanol 4 Unknown Status 1
DB00472 Fluoxetine 4 Completed 1
DB00472 Fluoxetine 4 Terminated 1
DB00996 Gabapentin 4 Terminated 1
DB04465 Lactose 4 Completed 1
DB00555 Lamotrigine 4 Completed 1
DB01202 Levetiracetam 4 Completed 1
DB00186 Lorazepam 4 Completed 2
DB00186 Lorazepam 4 Unknown Status 1
DB01043 Memantine 4 Completed 1
DB00422 Methylphenidate 4 Completed 1
DB00683 Midazolam 4 Withdrawn 1
DB06230 Nalmefene 4 Completed 1
DB06230 Nalmefene 4 Terminated 1
DB00704 Naltrexone 4 Completed 33
DB00704 Naltrexone 4 Recruiting 1
DB00704 Naltrexone 4 Terminated 3
DB00704 Naltrexone 4 Unknown Status 1
DB00184 Nicotine 4 Completed 6
DB00842 Oxazepam 4 Completed 1
DB00715 Paroxetine 4 Completed 1
DB00457 Prazosin 4 Completed 1
DB00230 Pregabalin 4 Completed 1
DB00818 Propofol 4 Withdrawn 1
DB01224 Quetiapine 4 Completed 2
DB00811 Ribavirin 4 Completed 1
DB01104 Sertraline 4 Completed 2
DB09072 Sodium oxybate 4 Completed 2
DB00421 Spironolactone 4 Suspended 1
DB00273 Topiramate 4 Completed 4
DB00273 Topiramate 4 Unknown Status 1
DB00313 Valproic acid 4 Unknown Status 1
DB01273 Varenicline 4 Completed 1
DB00909 Zonisamide 4 Completed 1
DB00659 Acamprosate Not Available Completed 1
DB00659 Acamprosate Not Available Terminated 1
DB00126 Ascorbic acid Not Available Completed 1
DB00126 Ascorbic acid Not Available Unknown Status 1
DB00201 Caffeine Not Available Recruiting 1
DB06724 Calcium carbonate Not Available Unknown Status 1
DB00190 Carbidopa Not Available Recruiting 1
DB00169 Cholecalciferol Not Available Unknown Status 1
DB00122 Choline Not Available Unknown Status 1
DB14529 Chromium nicotinate Not Available Unknown Status 1
DB00215 Citalopram Not Available Completed 1
DB00115 Cyanocobalamin Not Available Unknown Status 1
DB00260 Cycloserine Not Available Completed 1
DB14477 DL-alpha tocopheryl acetate Not Available Unknown Status 1
DB01576 Dextroamphetamine Not Available Recruiting 1
DB00829 Diazepam Not Available Completed 1
DB01075 Diphenhydramine Not Available Recruiting 1
DB00822 Disulfiram Not Available Completed 1
DB01126 Dutasteride Not Available Completed 2
DB00898 Ethanol Not Available Completed 3
DB00898 Ethanol Not Available Recruiting 2
DB14491 Ferrous fumarate Not Available Unknown Status 1
DB00158 Folic acid Not Available Unknown Status 1
DB00996 Gabapentin Not Available Completed 1
DB00145 Glycine Not Available Completed 1
DB11895 Lenomorelin Not Available Completed 1
DB01235 Levodopa Not Available Recruiting 1
DB01377 Magnesium oxide Not Available Unknown Status 1
DB06757 Manganese Not Available Unknown Status 1
DB00745 Modafinil Not Available Recruiting 1
DB11137 Molybdenum Not Available Unknown Status 1
DB06230 Nalmefene Not Available Active Not Recruiting 1
DB06230 Nalmefene Not Available Completed 1
DB00704 Naltrexone Not Available Completed 1
DB00704 Naltrexone Not Available Recruiting 1
DB00704 Naltrexone Not Available Unknown Status 1
DB02701 Nicotinamide Not Available Unknown Status 1
DB06715 Potassium Iodide Not Available Unknown Status 1
DB00457 Prazosin Not Available Terminated 1
DB00165 Pyridoxine Not Available Unknown Status 1
DB00140 Riboflavin Not Available Unknown Status 1
DB11135 Selenium Not Available Unknown Status 1
DB15049 Sucralose Not Available Recruiting 1
DB00795 Sulfasalazine Not Available Completed 1
DB00152 Thiamine Not Available Unknown Status 1
DB00599 Thiopental Not Available Completed 1
DB00273 Topiramate Not Available Terminated 1
DB00313 Valproic acid Not Available Completed 1
DB01273 Varenicline Not Available Completed 1
DB00162 Vitamin A Not Available Unknown Status 1
DB09321 Zinc oxide Not Available Unknown Status 1
DB00909 Zonisamide Not Available Completed 1