Alkaloids

Name
Alkaloids
Accession Number
DBCAT000443
Description

Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)

Drugs
Drug Drug Description
Caffeine A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
Reserpine For the treatment of hypertension
Benzatropine 一个一个ticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
Morphine An opioid agonist used for the relief of moderate to severe acute and chronic pain.
Vindesine A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
Hydromorphone An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
Ipratropium 一个一个ticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
Vinorelbine A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
Hyoscyamine 一个一个ticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
Quinine An alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
Oxycodone An opioid used in the management of moderate to severe pain.
Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough.
Vincristine A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Vinblastine A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
Lisuride For the management of Parkinson's Disease
Galantamine A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
Apomorphine A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
Scopolamine 颠茄生物碱有抗胆碱能作用indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV).
Irinotecan 一个一个tineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Pentoxifylline A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Hydrocodone An opioid agonist used as an analgesic and antitussive agent.
Dimenhydrinate A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness.
Topotecan 一个一个tineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
Pilocarpine A muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy.
Papaverine An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
Naloxone An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
Pergolide A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy.
Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
Colchicine An alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF).
Tiotropium A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
Duvoglustat An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Arecoline An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the...
Camptothecin Investigated for the treatment of cancer.
Omacetaxine mepesuccinate A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
Noscapine A non-sedating isoquinoline alkaloid used primarily for its antitussive properties.
Sparteine Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category...
Drotaverine A phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
Homatropine 一个一个ticholinergic agent used to dilate the pupil, treat inflammation of the uveal tract, and suppress a cough.
Vinflunine A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
Zalypsis Zalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others.
Samidorphan A novel opioid-system modulator, similar to naltrexone, that functions primarily as a μ-opioid receptor antagonist in vivo and is used primarily in combination with antipsychotics to reduce their metabolic dysfunction-associated adverse effects.
Sacituzumab govitecan Sacituzumab govitecan targets TROP-2-expressing cancer cells through a humanized antibody (RS7) before subsequently becoming internalized and releasing the topoisomerase I inhibitor SN-38 to induce DNA damage-mediated apoptosis.
Emetine Not Annotated
Colchiceine Colchiceine is one of several metabolites of the anti-gout medication colchicine.
Variolin B Not Available
1-deoxymannojirimycin An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem]
beta-Isosparteine Not Annotated
Ajmaline 一个一个tiarrhythmic used to manage a variety of forms of tachycardias.
K-252a Not Available
Lobeline Investigated for use/treatment in addictions.
Rauwolfia serpentina root Rauwolfia alkaloids are indicated in the treatment of hypertension . Rauwolfia alkaloids have been used for relief of symptoms in agitated psychotic states such as schizophrenia; however, use as antipsychotics...
Metoserpate Not Annotated
Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Tetrandrine Not Annotated
Raubasine Not Annotated
Nicotine A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
Methysergide An ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
Methylergometrine An ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery.
Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
Miglustat A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
Methscopolamine bromide 毒蕈碱的拮抗剂用于治疗消化性溃疡s, nausea, vomiting, and motion sickness.
Miglitol An oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
Levallorphan For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.
Anisotropine methylbromide For use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying.
Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain.
Pentazocine 一个一个algesic used to treat moderate to severe pain.
Ergotamine An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
Nicergoline An ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities.
Naltrexone A narcotic antagonist used in opioid overdose.
Homatropine methylbromide A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
Cryptenamine For the treatment of hypertension.
Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Nalbuphine An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery.
Levorphanol An opioid analgesic used to treat moderate to severe pain.
Buprenorphine A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
Physostigmine A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
Ergoloid mesylate A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Deserpidine An alkaloid that has been used to manage hypertension.
Rescinnamine For the treatment of hypertension.
Oxymorphone An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies.
Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
Ergometrine An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony.
Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
Metocurine Metocurine is a muscle relaxant.
Yohimbine An alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
Almitrine For the treatment of chronic obstructive pulmonary disease.
5-Methoxy-N,N-diisopropyltryptamine 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a...
Dihydroetorphine Not Available
Diamorphine 的阿片类止痛剂用于救灾vere pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema.
Ethylmorphine An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine.
Cyprenorphine Not Available
Fenethylline Not Available
Etorphine Etorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals.
Benzoylecgonine Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after...
Ecgonine Not Available
Desomorphine Not Available
Drotebanol Not Available
Diprenorphine Diprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans.
Dihydrocodeine An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Dihydromorphine Dihydromorphine is an opioid analgesic used for moderate to severe pain relief.
Tropinone Not Available
8-azaxanthine Not Available
7-Hydroxystaurosporine Not Available
Staurosporine An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Xanthine A drug used to manage uncomplicated liver dysfunction in combination with orotic acid.
Deacetoxyvinzolidine Not Available
Pseudotropine Not Available
Berberine An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal...
Calystegine B2 Not Available
Methylecgonine Not Available
Lysergic acid diethylamide Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by...
Voacamine For the treatment of malaria. Also under investigation for the modulation of multidrug resistance in cancer cells.
Phenserine For the treatment of Alzheimer's disease (AD).
Altropane Investigated for use/treatment in attention deficit/hyperactivity disorder (ADHD), parkinson's disease, and pediatric indications.
Migalastat An alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
Vintafolide Investigated for use/treatment in solid tumors.
7-ethyl-10-hydroxycamptothecin 调查/治疗结直肠通过使用r.
NS-2359 Investigated for use/treatment in addictions, attention deficit/hyperactivity disorder (ADHD), and depression.
Cositecan Investigated for use/treatment in brain cancer, lung cancer, and melanoma.
Rivanicline Investigated for use/treatment in ulcerative colitis.
CRLX101 Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
XMT-1001 Investigated for use/treatment in solid tumors.
Rubitecan Investigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
Nalmefene An opioid antagonist used to reduce alcohol consumption in adults with alcohol dependence and treat and prevent opioid overdose.
Morphine glucuronide Investigated for use/treatment in pain (acute or chronic).
Naxifylline Investigated for use/treatment in congestive heart failure.
Propentofylline Investigated for use/treatment in alzheimer's disease.
Midostaurin 一个一个tineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
Gimatecan Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
Harmine Not Available
Ioflupane I-123 A radiopharmaceutical used in single photon emission computed tomography (SPECT) brain imaging to help diagnose patients with suspected Parkinsonian syndromes.
Uric acid At present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke.
Aclidinium An inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD).
Fentonium Fentonium is an atropine derivative.
Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
Pholcodine An opioid antitussive used to suppress unproductive coughing.
Cimetropium Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which...
Doxofylline A methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms.
Butylscopolamine 一个一个tispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain.
Dihydroergocornine A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Epicriptine A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Methscopolamine Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The...
Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
Nalorphine Used to reverse opioid overdose.
Bicuculline Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and...
Thiocolchicoside A semi-synthetic colchicine derivative used as an analgesic and anti-inflammatory.
Psilocybin Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Naldemedine An opioid antagonist used to to treat opioid-induced constipation.
Anisodamine 已经调查了应用山莨菪碱t of Intestinal Diseases.
Axelopran Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
Orantinib Orantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others.
Oxitropium Oxitropium has been investigated for the treatment of Pulmonary Disease, Chronic Obstructive.
Tetrahydropalmatine 延胡索乙素我s under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
Namitecan Namitecan has been used in trials studying the treatment of Solid Tumors.
Vinpocetine A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
Exatecan Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Lurtotecan Lurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
Moxaverine Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.
Silatecan Silatecan has been used in trials studying the treatment of GBM, Tumors, Gliosarcoma, Solid Malignancies, and Glioblastoma Multiforme, among others.
10-hydroxycamptothecin 10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).
Belotecan Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
9-aminocamptothecin Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Tonapofylline Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
Patidegib Patidegib has been investigated for the treatment of Conventional Chondrosarcoma.
Rolofylline Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
Solamargine Solamargine has been used in trials studying the treatment of Actinic Keratosis.
Pegamotecan Pegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
Reproterol A short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma.
Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
8-cyclopentyl-1,3-dipropylxanthine CPX has been used in trials studying the treatment of Cystic Fibrosis.
CT-2584 CT-2584 has been used in trials studying the treatment of Prostate Cancer.
Ambroxol acefyllinate A bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm.
Bamifylline A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm.
Demecolcine Not Annotated
Dihydroergocristine An ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
Vincamine Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
Dihydroergocryptine A dopamine agonist indicated in the treatment of cerebrovascular diseases and atherosclerosis.
Terguride Not Annotated
Proxyphylline Not Annotated
Nicomorphine Not Annotated
Deptropine Not Annotated
Etybenzatropine Not Annotated
Nalfurafine Not Annotated
Tenidap Not Annotated
Metergoline An ergot-derivative that acts as an antagonist at certain 5-HT receptor subtypes and as an agonist at dopamine receptors. It is often used in situations where inhibition of prolactin is desirable.
Prajmaline Not Annotated
Acefylline Not Annotated
Bietaserpine Not Annotated
Etamiphylline Not Annotated
Phenazocine Not Annotated
Pentifylline Not Annotated
Lorajmine Not Annotated
Hydroquinine Not Annotated
Vinburnine Not Annotated
Dimemorfan Not Annotated
Bufylline Not Annotated
Methylatropine Not Annotated
Dehydroemetine Not Annotated
Harmaline Not Annotated
Bromotheophylline Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
Furafylline Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
8-chlorotheophylline When used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
Loxicodegol Loxicodegol was developed as an opioid analgesic with low abuse potential for use in treating chronic pain . An application has been filed for FDA approval of Loxicodegol for use...
Dextrorphan Not Annotated
PF-232798 PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Lucerastat Lucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
Firtecan pegol Firtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).
18-methoxycoronaridine 18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
Hydroquinidine A medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm.
Posiphen Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate).
Strychnine Not Annotated
Butropium A medication indicated to treat pain caused by gastrointestinal inflammation and ulcers, or diseases of the gallbladder.
Diflomotecan Diflomotecan is under investigation in clinical trial NCT00080015 (Diflomotecan (BN80915) Administered Once Every 3 Weeks in Treating Patients With Sensitive Small Cell Lung Cancer (SCLC)).
Nazartinib Nazartinib is under investigation in clinical trial NCT03529084 (Phase III Study of Nazartinib (EGF816) Versus Erlotinib/gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations).
Dihydroergotoxine Not Annotated
Cepharanthine Not Annotated
Cinchonidine Not Annotated
Sinomenine Not Annotated
Ioflupane F-18 Not Annotated
Chelerythrine 作为基那benzophenanthridine生物碱评估se-inhibitor.
Ellipticine Ellipticine is a potent antineoplastic agent.
Solasonine Not Annotated
Ukrain cation Not Annotated
DRF-1042 Not Annotated
Lipotecan Not Annotated
Gibberellic acid Not Available
Gibberellin A4 Not Available
Cytisine An alkaloid with partial agonist activity at the α4β2 nicotinic acetylcholine receptor used to aid smoking cessation.
Salvinorin A Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations.
Steviolbioside Steviolbioside has been used in trials studying the treatment of HIV-1 Infection.
Rebaudioside A Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).
Oxymatrine Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).
Isosteviol Not Annotated
Stevioside Not Annotated
Intermedine Not Annotated
Drugs & Drug Targets
Drug Target Type
Caffeine Adenosine receptor A1 target
Caffeine cAMP-specific 3',5'-cyclic phosphodiesterase 4B target
Caffeine Adenosine receptor A2a target
Caffeine Cytochrome P450 1A2 enzyme
Caffeine Ryanodine receptor 1 target
Caffeine Cytochrome P450 3A4 enzyme
Caffeine Cytochrome P450 2E1 enzyme
Caffeine Cytochrome P450 2C8 enzyme
Caffeine Cytochrome P450 2C9 enzyme
Caffeine Cytochrome P450 1A1 enzyme
Caffeine Cytochrome P450 1B1 enzyme
Caffeine Cytochrome P450 2D6 enzyme
Caffeine Cyclic nucleotide phosphodiesterase target
Caffeine DNA-dependent protein kinase catalytic subunit target
Caffeine Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform target
Caffeine Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform target
Caffeine Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform target
Caffeine Inositol 1,4,5-trisphosphate receptor target
Caffeine Serine-protein kinase ATM target
Caffeine ATP-binding cassette sub-family G member 2 transporter
Caffeine Adenosine receptor A2b target
Caffeine Adenosine receptor A3 target
Caffeine Phosphodiesterase enzymes target
Reserpine Synaptic vesicular amine transporter target
Reserpine P-glycoprotein 1 transporter
Reserpine Solute carrier family 22 member 1 transporter
Reserpine Bile salt export pump transporter
Reserpine Canalicular multispecific organic anion transporter 1 transporter
Reserpine Solute carrier family 22 member 2 transporter
Reserpine Cytochrome P450 3A5 enzyme
Reserpine Chromaffin granule amine transporter target
Reserpine Baculoviral IAP repeat-containing protein 5 target
Reserpine Solute carrier organic anion transporter family member 1B1 transporter
Reserpine Solute carrier organic anion transporter family member 2B1 transporter
Benzatropine Muscarinic acetylcholine receptor M1 target
Benzatropine Sodium-dependent dopamine transporter target
Benzatropine Histamine H1 receptor target
Benzatropine Serum albumin carrier
Benzatropine Sodium-dependent serotonin transporter target
Benzatropine Sodium-dependent noradrenaline transporter target
Cabergoline Dopamine D2 receptor target
Cabergoline 5-hydroxytryptamine receptor 2B target
Cabergoline Dopamine D3 receptor target
Cabergoline 5-hydroxytryptamine receptor 2A target
Cabergoline Alpha-2B adrenergic receptor target
Cabergoline 5-hydroxytryptamine receptor 1D target
Cabergoline Dopamine D4 receptor target
Cabergoline Alpha-2A adrenergic receptor target
Cabergoline 5-hydroxytryptamine receptor 1A target
Cabergoline Alpha-2C adrenergic receptor target
Cabergoline Dopamine D5 receptor target
Cabergoline 多巴胺D1受体 target
Cabergoline 5-hydroxytryptamine receptor 1B target
Cabergoline 5-hydroxytryptamine receptor 2C target
Cabergoline Cytochrome P450 3A4 enzyme
Cabergoline 5-hydroxytryptamine receptor 7 target
Cabergoline Alpha-1A adrenergic receptor target
Cabergoline Alpha-1B adrenergic receptor target
Cabergoline Alpha-1D adrenergic receptor target
Cabergoline Beta-1 adrenergic receptor target
Cabergoline Beta-2 adrenergic receptor target
Cabergoline D(1) dopamine receptor target
Cabergoline P-glycoprotein 1 transporter
Morphine Mu-type opioid receptor target
Morphine Delta-type opioid receptor target
Morphine Kappa-type opioid receptor target
Morphine P-glycoprotein 1 transporter
Morphine Cytochrome P450 2C8 enzyme
Morphine Cytochrome P450 3A4 enzyme
Morphine UDP-glucuronosyltransferase 2B7 enzyme
Morphine UDP-glucuronosyltransferase 1-1 enzyme
Morphine UDP-glucuronosyltransferase 1-8 enzyme
Morphine UDP-glucuronosyltransferase 2B15 enzyme
Morphine UDP-glucuronosyltransferase 2B4 enzyme
Morphine UDP-glucuronosyltransferase 1-3 enzyme
Morphine Lymphocyte antigen 96 target
Morphine Serum albumin carrier
Vindesine Tubulin beta-1 chain target
Vindesine Cytochrome P450 3A4 enzyme
Codeine Mu-type opioid receptor target
Codeine Delta-type opioid receptor target
Codeine Kappa-type opioid receptor target
Codeine Cytochrome P450 2D6 enzyme
Codeine Cytochrome P450 3A4 enzyme
Codeine Solute carrier family 22 member 1 transporter
Codeine UDP-glucuronosyltransferase 2B7 enzyme
Codeine UDP-glucuronosyltransferase 2B4 enzyme
Dihydroergotamine 5-hydroxytryptamine receptor 1D target
Dihydroergotamine 5-hydroxytryptamine receptor 1B target
Dihydroergotamine Cytochrome P450 3A4 enzyme
Dihydroergotamine Alpha-2A adrenergic receptor target
Dihydroergotamine 5-hydroxytryptamine receptor 2B target
Dihydroergotamine P-glycoprotein 1 transporter
Dihydroergotamine 5-hydroxytryptamine receptor 1A target
Dihydroergotamine 5-hydroxytryptamine receptor 1E target
Dihydroergotamine 5-hydroxytryptamine receptor 2A target
Dihydroergotamine 5-hydroxytryptamine receptor 2C target
Dihydroergotamine Alpha-1 adrenergic receptors target
Dihydroergotamine Alpha-2 adrenergic receptors target
Dihydroergotamine Dopamine D2 receptor target
Dihydroergotamine Dopamine D3 receptor target
Dihydroergotamine Dopamine D4 receptor target
Dihydroergotamine 5-hydroxytryptamine receptor 1F target
Dihydroergotamine 5-hydroxytryptamine receptor 4 target
Dihydroergotamine Beta-3 adrenergic receptor target
Hydromorphone Mu-type opioid receptor target
Hydromorphone Delta-type opioid receptor target
Hydromorphone Kappa-type opioid receptor target
Hydromorphone Cytochrome P450 2C9 enzyme
Hydromorphone UDP-glucuronosyltransferase 1-3 enzyme
Hydromorphone UDP-glucuronosyltransferase 2B7 enzyme
Hydromorphone Serum albumin carrier
Ipratropium Muscarinic acetylcholine receptor M1 target
Ipratropium Muscarinic acetylcholine receptor M2 target
Ipratropium Muscarinic acetylcholine receptor M3 target
Ipratropium Solute carrier family 22 member 5 transporter
Ipratropium Solute carrier family 22 member 4 transporter
Ipratropium Serum albumin carrier
Ipratropium alpha1-acid glycoprotein carrier
Vinorelbine Tubulin beta chain target
Vinorelbine Cytochrome P450 3A4 enzyme
Vinorelbine Cytochrome P450 2D6 enzyme
Hyoscyamine Muscarinic acetylcholine receptor M1 target
Hyoscyamine Muscarinic acetylcholine receptor M2 target
Hyoscyamine Muscarinic acetylcholine receptor M3 target
Hyoscyamine Muscarinic acetylcholine receptor M4 target
Hyoscyamine Adenylate cyclase type 1 target
Quinine Platelet glycoprotein IX target
Quinine Intermediate conductance calcium-activated potassium channel protein 4 target
Quinine Cytochrome P450 3A4 enzyme
Quinine Cytochrome P450 3A5 enzyme
Quinine Cytochrome P450 1A1 enzyme
Quinine Cytochrome P450 2D6 enzyme
Quinine Cytochrome P450 1A2 enzyme
Quinine Cytochrome P450 2C8 enzyme
Quinine Cytochrome P450 2C9 enzyme
Quinine Cytochrome P450 2C19 enzyme
Quinine Cytochrome P450 2E1 enzyme
Quinine Cytochrome P450 3A7 enzyme
Quinine Solute carrier family 22 member 2 transporter
Quinine Solute carrier family 22 member 1 transporter
Quinine Solute carrier family 22 member 5 transporter
Quinine P-glycoprotein 1 transporter
Quinine Solute carrier organic anion transporter family member 1A2 transporter
Quinine Solute carrier family 22 member 4 transporter
Quinine Fe(II)-protoporphyrin IX target
Quinine Solute carrier organic anion transporter family member 1B1 transporter
Oxycodone Mu-type opioid receptor target
Oxycodone Kappa-type opioid receptor target
Oxycodone Delta-type opioid receptor target
Oxycodone Cytochrome P450 2D6 enzyme
Oxycodone Cytochrome P450 3A4 enzyme
Oxycodone Cytochrome P450 3A5 enzyme
Oxycodone Serum albumin carrier
Oxycodone alpha1-acid glycoprotein carrier
Dextromethorphan Sigma non-opioid intracellular receptor 1 target
Dextromethorphan Neuronal acetylcholine receptor subunit alpha-2 target
Dextromethorphan Sodium-dependent serotonin transporter target
Dextromethorphan Glutamate receptor ionotropic, NMDA 3A target
Dextromethorphan Cytochrome P450 2D6 enzyme
Dextromethorphan Cytochrome P450 3A4 enzyme
Dextromethorphan Cytochrome P450 3A7 enzyme
Dextromethorphan Cytochrome P450 2C9 enzyme
Dextromethorphan Cytochrome P450 2B6 enzyme
Dextromethorphan Cytochrome P450 2C19 enzyme
Dextromethorphan Membrane-associated progesterone receptor component 1 target
Dextromethorphan Neuronal acetylcholine receptor subunit alpha-3 target
Dextromethorphan Neuronal acetylcholine receptor subunit alpha-4 target
Dextromethorphan Neuronal acetylcholine receptor subunit beta-4 target
Dextromethorphan Neuronal acetylcholine receptor subunit beta-2 target
Dextromethorphan Neuronal acetylcholine receptor subunit alpha-7 target
Dextromethorphan Mu-type opioid receptor target
Dextromethorphan Delta-type opioid receptor target
Dextromethorphan Kappa-type opioid receptor target
Dextromethorphan NADPH oxidase target
Dextromethorphan Sodium-dependent noradrenaline transporter target
Dextromethorphan UDP-glucuronosyltransferase 2B4 enzyme
Dextromethorphan UDP-glucuronosyltransferase 2B7 enzyme
Dextromethorphan UDP-glucuronosyltransferase 2B15 enzyme
Dextromethorphan UDP-glucuronosyltransferase 2B17 enzyme
Vincristine Tubulin beta chain target
Vincristine Cytochrome P450 3A4 enzyme
Vincristine Cytochrome P450 3A5 enzyme
Vincristine Cytochrome P450 3A7 enzyme
Vincristine P-glycoprotein 1 transporter
Vincristine Canalicular multispecific organic anion transporter 2 transporter
Vincristine Solute carrier family 22 member 3 transporter
Vincristine Multidrug resistance-associated protein 1 transporter
Vincristine Multidrug resistance-associated protein 7 transporter
Vincristine Canalicular multispecific organic anion transporter 1 transporter
Vincristine Bile salt export pump transporter
Vincristine ATP-binding cassette sub-family G member 2 transporter
Vincristine Tubulin alpha-4A chain target
Vincristine RalA-binding protein 1 transporter
Vincristine Solute carrier organic anion transporter family member 1B1 transporter
Vincristine Solute carrier organic anion transporter family member 1B3 transporter
Vinblastine Tubulin beta chain target
Vinblastine Transcription factor AP-1 target
Vinblastine Cytochrome P450 3A4 enzyme
Vinblastine P-glycoprotein 1 transporter
Vinblastine Multidrug resistance-associated protein 1 transporter
Vinblastine Canalicular multispecific organic anion transporter 1 transporter
Vinblastine Multidrug resistance-associated protein 6 transporter
Vinblastine Bile salt export pump transporter
Vinblastine Tubulin alpha-1A chain target
Vinblastine Tubulin delta chain target
Vinblastine Tubulin epsilon chain target
Vinblastine Tubulin gamma-1 chain target
Vinblastine Cytochrome P450 2D6 enzyme
Vinblastine Solute carrier organic anion transporter family member 1B1 transporter
Atropine Muscarinic acetylcholine receptor M2 target
Atropine Muscarinic acetylcholine receptor M1 target
Atropine Muscarinic acetylcholine receptor M4 target
Atropine Muscarinic acetylcholine receptor M5 target
Atropine Muscarinic acetylcholine receptor M3 target
Atropine Glycine receptor subunit alpha-1 target
Atropine Neuronal acetylcholine receptor subunit alpha-4 target
Atropine Neuronal acetylcholine receptor subunit beta-2 target
Atropine Bile salt export pump transporter
Atropine Alpha-1-acid glycoprotein 1 carrier
Lisuride 多巴胺D1受体 target
Lisuride 5-hydroxytryptamine receptor 1A target
Lisuride Dopamine D2 receptor target
Lisuride Alpha-2A adrenergic receptor target
Lisuride Alpha-2B adrenergic receptor target
Lisuride Alpha-2C adrenergic receptor target
Lisuride Dopamine D3 receptor target
Lisuride 5-hydroxytryptamine receptor 1D target
Lisuride 5-hydroxytryptamine receptor 2B target
Lisuride 5-hydroxytryptamine receptor 2A target
Lisuride Dopamine D4 receptor target
Lisuride 5-hydroxytryptamine receptor 2C target
Lisuride Dopamine D5 receptor target
Lisuride 5-hydroxytryptamine receptor 1B target
Lisuride Cytochrome P450 3A4 enzyme
Lisuride 5-hydroxytryptamine receptor 7 target
Galantamine Acetylcholinesterase target
Galantamine Cytochrome P450 3A4 enzyme
Galantamine Cytochrome P450 2D6 enzyme
Galantamine Cholinesterase target
Galantamine P-glycoprotein 1 transporter
Galantamine Neuronal acetylcholine receptor subunit alpha-7 target
Galantamine Muscle nicotinic acetylcholine receptor target
Apomorphine Dopamine D2 receptor target
Apomorphine 多巴胺D1受体 target
Apomorphine Dopamine D4 receptor target
Apomorphine Dopamine D3 receptor target
Apomorphine Dopamine D5 receptor target
Apomorphine Alpha-2C adrenergic receptor target
Apomorphine Alpha-2B adrenergic receptor target
Apomorphine 5-hydroxytryptamine receptor 2C target
Apomorphine 5-hydroxytryptamine receptor 1A target
Apomorphine 5-hydroxytryptamine receptor 2A target
Apomorphine 5-hydroxytryptamine receptor 2B target
Apomorphine Alpha-2A adrenergic receptor target
Apomorphine 5-hydroxytryptamine receptor 1D target
Apomorphine 5-hydroxytryptamine receptor 1B target
Apomorphine Catechol O-methyltransferase enzyme
Apomorphine Sulfotransferase 1A1 enzyme
Apomorphine Sulfotransferase 1A2 enzyme
Apomorphine Sulfotransferase 1A3/1A4 enzyme
Apomorphine Estrogen sulfotransferase enzyme
Apomorphine Sulfotransferase family cytosolic 1B member 1 enzyme
Apomorphine Cytochrome P450 2B6 enzyme
Apomorphine Cytochrome P450 2C8 enzyme
Apomorphine Cytochrome P450 3A4 enzyme
Apomorphine Cytochrome P450 3A5 enzyme
Apomorphine UDP-glucuronosyltransferases (UGTs) enzyme
Apomorphine Serum albumin carrier
Apomorphine Synaptic vesicular amine transporter transporter
Scopolamine Muscarinic acetylcholine receptor M1 target
Scopolamine Sucrase-isomaltase, intestinal target
Scopolamine Muscarinic acetylcholine receptor M2 target
Scopolamine Muscarinic acetylcholine receptor M3 target
Scopolamine Muscarinic acetylcholine receptor M4 target
Scopolamine Muscarinic acetylcholine receptor M5 target
Scopolamine Neuronal acetylcholine receptor subunit alpha-4 target
Scopolamine Neuronal acetylcholine receptor subunit beta-2 target
Scopolamine Cytochrome P450 3A4 enzyme
Irinotecan DNA topoisomerase I, mitochondrial target
Irinotecan DNA topoisomerase 1 target
Irinotecan Cytochrome P450 3A4 enzyme
Irinotecan Cytochrome P450 3A5 enzyme
Irinotecan UDP-glucuronosyltransferase 1-1 enzyme
Irinotecan UDP-glucuronosyltransferase 1-9 enzyme
Irinotecan Liver carboxylesterase 1 enzyme
Irinotecan Cytochrome P450 3A7 enzyme
Irinotecan Cytochrome P450 2B6 enzyme
Irinotecan Solute carrier family 22 member 3 transporter
Irinotecan Solute carrier organic anion transporter family member 1B1 transporter
Irinotecan Multidrug resistance-associated protein 1 transporter
Irinotecan ATP-binding cassette sub-family G member 2 transporter
Irinotecan Serum albumin carrier
Irinotecan Cocaine esterase enzyme
Irinotecan Cholinesterase enzyme
Irinotecan P-glycoprotein 1 transporter
Irinotecan Canalicular multispecific organic anion transporter 1 transporter
Pentoxifylline 5 '核苷酸酶 target
Pentoxifylline Adenosine receptor A1 target
Pentoxifylline Adenosine receptor A2a target
Pentoxifylline Cytochrome P450 1A2 enzyme
Pentoxifylline Phosphodiesterase enzymes target
Cocaine Sodium-dependent noradrenaline transporter target
Cocaine Sodium channel protein target
Cocaine Sodium-dependent serotonin transporter target
Cocaine Sodium-dependent dopamine transporter target
Cocaine Cytochrome P450 3A4 enzyme
Cocaine Muscarinic acetylcholine receptor M1 target
Cocaine Muscarinic acetylcholine receptor M2 target
Cocaine Cytochrome P450 2D6 enzyme
Cocaine Solute carrier family 22 member 2 transporter
Cocaine Cytochrome P450 2C8 enzyme
Cocaine Sigma non-opioid intracellular receptor 1 target
Cocaine Liver carboxylesterase 1 target
Cocaine Cholinesterase enzyme
Cocaine Sodium-dependent dopamine transporter transporter
Cocaine alpha1-acid glycoprotein carrier
Cocaine Liver carboxylesterase 1 enzyme
Quinidine Sodium channel protein type 5 subunit alpha target
Quinidine Alpha-1-acid glycoprotein 1 carrier
Quinidine Potassium voltage-gated channel subfamily H member 2 target
Quinidine Potassium channel subfamily K member 1 target
Quinidine Potassium channel subfamily K member 6 target
Quinidine Cytochrome P450 1A2 enzyme
Quinidine Cytochrome P450 2E1 enzyme
Quinidine Cytochrome P450 1A1 enzyme
Quinidine Cytochrome P450 2D6 enzyme
Quinidine Cytochrome P450 3A4 enzyme
Quinidine Cytochrome P450 3A7 enzyme
Quinidine Solute carrier family 22 member 2 transporter
Quinidine Solute carrier family 22 member 1 transporter
Quinidine Solute carrier family 22 member 5 transporter
Quinidine P-glycoprotein 1 transporter
Quinidine Solute carrier organic anion transporter family member 1A2 transporter
Quinidine Solute carrier family 22 member 8 transporter
Quinidine Canalicular multispecific organic anion transporter 1 transporter
Quinidine Solute carrier family 22 member 4 transporter
Quinidine Solute carrier organic anion transporter family member 1B1 transporter
Quinidine Cytochrome P450 2B6 enzyme
Quinidine Cytochrome P450 2C9 enzyme
Quinidine Alpha-1A adrenergic receptor target
Quinidine Alpha-1B adrenergic receptor target
Quinidine Alpha-1D adrenergic receptor target
Quinidine Bile salt export pump transporter
Quinidine Cytochrome P450 2C8 enzyme
Quinidine Serum albumin carrier
Hydrocodone Mu-type opioid receptor target
Hydrocodone Delta-type opioid receptor target
Hydrocodone Cytochrome P450 3A4 enzyme
Hydrocodone Cytochrome P450 2D6 enzyme
Hydrocodone Cytochrome P450 2B6 enzyme
Hydrocodone Cytochrome P450 2C19 enzyme
Hydrocodone Sigma non-opioid intracellular receptor 1 target
Dimenhydrinate Histamine H1 receptor target
Topotecan DNA topoisomerase I, mitochondrial target
Topotecan DNA topoisomerase 1 target
Topotecan ATP-binding cassette sub-family G member 2 transporter
Topotecan P-glycoprotein 1 transporter
Topotecan DNA target
Topotecan Multidrug and toxin extrusion protein 1 transporter
Topotecan Multidrug and toxin extrusion protein 2 transporter
Pilocarpine Muscarinic acetylcholine receptor M1 target
Pilocarpine Muscarinic acetylcholine receptor M2 target
Pilocarpine Cytochrome P450 2A6 enzyme
Pilocarpine Muscarinic acetylcholine receptor M3 target
Pilocarpine Cytochrome P450 3A4 enzyme
Pilocarpine Muscarinic acetylcholine receptor M4 target
Papaverine cAMP-specific 3',5'-cyclic phosphodiesterase 4B target
Papaverine cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A target
Papaverine Phosphodiesterase enzymes target
Naloxone Mu-type opioid receptor target
Naloxone Estrogen receptor alpha target
Naloxone Cyclic AMP-responsive element-binding protein 1 target
Naloxone Delta-type opioid receptor target
Naloxone Solute carrier organic anion transporter family member 1A2 transporter
Naloxone P-glycoprotein 1 transporter
Naloxone Kappa-type opioid receptor target
Naloxone Cytochrome P450 3A4 enzyme
Naloxone Serum albumin carrier
Naloxone Toll-like receptor 4 target
Naloxone Liver carboxylesterase 1 target
Naloxone UDP-glucuronosyltransferase 1-1 enzyme
Naloxone Cytochrome P450 2C18 enzyme
Naloxone Cytochrome P450 2C19 enzyme
Pergolide Dopamine D2 receptor target
Pergolide 多巴胺D1受体 target
Pergolide Dopamine D3 receptor target
Pergolide 5-hydroxytryptamine receptor 1A target
Pergolide Alpha-1A adrenergic receptor target
Pergolide Alpha-2 adrenergic receptors target
Pergolide Alpha-1B adrenergic receptor target
Pergolide Alpha-1D adrenergic receptor target
Pergolide Dopamine D4 receptor target
Pergolide Dopamine D5 receptor target
Pergolide 5-hydroxytryptamine receptor 1B target
Pergolide 5-hydroxytryptamine receptor 1D target
Pergolide 5-hydroxytryptamine receptor 2A target
Pergolide 5-hydroxytryptamine receptor 2B target
Pergolide 5-hydroxytryptamine receptor 2C target
Pergolide Cytochrome P450 3A4 enzyme
Tubocurarine Neuronal acetylcholine receptor subunit alpha-2 target
Tubocurarine Acetylcholinesterase target
Tubocurarine 5-hydroxytryptamine receptor 3A target
Tubocurarine Solute carrier family 22 member 1 transporter
Tubocurarine Solute carrier family 22 member 2 transporter
Tubocurarine Neuronal acetylcholine receptor subunit alpha-7 target
Tubocurarine Cholinesterase enzyme
Colchicine Tubulin beta chain target
Colchicine Cytochrome P450 3A4 enzyme
Colchicine P-glycoprotein 1 transporter
Colchicine Cytochrome P450 2B6 enzyme
Colchicine Cytochrome P450 2C8 enzyme
Colchicine Cytochrome P450 2E1 enzyme
Colchicine Serum albumin carrier
Tiotropium Muscarinic acetylcholine receptor M3 target
Tiotropium Cytochrome P450 2D6 enzyme
Tiotropium Cytochrome P450 3A4 enzyme
Tiotropium Muscarinic acetylcholine receptor M1 target
Tiotropium Muscarinic acetylcholine receptor M2 target
Tiotropium Solute carrier family 22 member 5 transporter
Tiotropium Solute carrier family 22 member 4 transporter
Tiotropium Muscarinic acetylcholine receptor M4 target
Tiotropium Muscarinic acetylcholine receptor M5 target
Duvoglustat Cyclomaltodextrin glucanotransferase target
Duvoglustat Beta-glucosidase A target
Duvoglustat Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase target
Duvoglustat Mannosyl-oligosaccharide alpha-1,2-mannosidase target
Duvoglustat Xylose isomerase target
Arecoline Muscarinic acetylcholine receptor M1 target
Arecoline Muscarinic acetylcholine receptor M3 target
Camptothecin DNA topoisomerase 1 target
Camptothecin P-glycoprotein 1 transporter
Camptothecin ATP-binding cassette sub-family G member 2 transporter
Camptothecin Serum albumin carrier
Omacetaxine mepesuccinate 50S ribosomal protein L2 target
Omacetaxine mepesuccinate 60S ribosomal protein L3 target
Noscapine Sigma non-opioid intracellular receptor 1 target
Noscapine Cytochrome P450 2C9 enzyme
Noscapine Cytochrome P450 3A4 enzyme
Sparteine Cytochrome P450 2D6 enzyme
Drotaverine cAMP-specific 3',5'-cyclic phosphodiesterase 4A target
Drotaverine Voltage-dependent L-type calcium channel target
Homatropine Liver carboxylesterase 1 enzyme
Homatropine Muscarinic acetylcholine receptor M1 target
Homatropine Muscarinic acetylcholine receptor M2 target
Homatropine Muscarinic acetylcholine receptor M3 target
Homatropine Muscarinic acetylcholine receptor M4 target
Homatropine Muscarinic acetylcholine receptor M5 target
Vinflunine ATP-binding cassette sub-family B member 5 transporter
Vinflunine P-glycoprotein 1 transporter
Vinflunine Serum albumin carrier
Vinflunine alpha1-acid glycoprotein carrier
Vinflunine Cytochrome P450 3A4 enzyme
Vinflunine Tubulin beta chain target
Samidorphan Mu-type opioid receptor target
Samidorphan Kappa-type opioid receptor target
Samidorphan Delta-type opioid receptor target
Samidorphan Cytochrome P450 3A4 enzyme
Samidorphan Cytochrome P450 3A5 enzyme
Samidorphan Cytochrome P450 2C19 enzyme
Samidorphan Cytochrome P450 2C8 enzyme
Sacituzumab govitecan Tumor-associated calcium signal transducer 2 target
Sacituzumab govitecan DNA topoisomerase 1 target
Sacituzumab govitecan Far upstream element-binding protein 1 target
Sacituzumab govitecan UDP-glucuronosyltransferase 1-1 enzyme
Colchiceine Tubulin beta chain target
Colchiceine Tubulin alpha-1A chain target
Colchiceine Serum albumin carrier
Variolin B Cyclin-dependent kinase 2 target
Variolin B Cyclin-A2 target
1-deoxymannojirimycin Alpha-mannosidase 2 target
Ajmaline Alpha-1-acid glycoprotein 1 carrier
Ajmaline Sodium channel protein type 5 subunit alpha target
K-252a Hepatocyte growth factor receptor target
K-252a Dual specificity mitogen-activated protein kinase kinase 1 target
Lobeline Neuronal acetylcholine receptor subunit alpha-9 target
Lobeline Neuronal acetylcholine receptor subunit alpha-10 target
Lobeline Neuronal acetylcholine receptor subunit alpha-7 target
Rauwolfia serpentina root Synaptic vesicular amine transporter target
Rauwolfia serpentina root Monoamine oxidase enzyme
Rauwolfia serpentina root Sodium-dependent noradrenaline transporter transporter
Rauwolfia serpentina root vesicular monoamine transporter 2 (VMAT2) transporter
Tetrandrine P-glycoprotein 1 target
Tetrandrine Cytochrome P450 3A4 enzyme
Tetrandrine P-glycoprotein 1 transporter
Nicotine Neuronal acetylcholine receptor subunit alpha-2 target
Nicotine Neuronal acetylcholine receptor subunit beta-2 target
Nicotine Neuronal acetylcholine receptor subunit alpha-7 target
Nicotine Neuronal acetylcholine receptor subunit alpha-4 target
Nicotine Neuronal acetylcholine receptor subunit alpha-10 target
Nicotine Neuronal acetylcholine receptor subunit alpha-9 target
Nicotine Cytochrome P450 2A6 enzyme
Nicotine Cytochrome P450 2E1 enzyme
Nicotine Cytochrome P450 2A13 enzyme
Nicotine Cytochrome P450 2B6 enzyme
Nicotine Neuronal acetylcholine receptor subunit beta-4 target
Nicotine Neuronal acetylcholine receptor subunit alpha-3 target
Nicotine Neuronal acetylcholine receptor subunit alpha-5 target
Nicotine Neuronal acetylcholine receptor subunit alpha-6 target
Nicotine Neuronal acetylcholine receptor subunit beta-3 target
Nicotine Solute carrier family 22 member 2 transporter
Nicotine Solute carrier family 22 member 1 transporter
Nicotine Solute carrier family 22 member 3 transporter
Nicotine Solute carrier family 22 member 5 transporter
Nicotine Solute carrier family 22 member 4 transporter
Nicotine Cytochrome P450 1A1 enzyme
Nicotine Cytochrome P450 1A2 enzyme
Nicotine Cytochrome P450 2C19 enzyme
Nicotine Cytochrome P450 2C8 enzyme
Nicotine Cytochrome P450 2C9 enzyme
Nicotine Cytochrome P450 2D6 enzyme
Nicotine Cytochrome P450 3A4 enzyme
Nicotine Amine oxidase [flavin-containing] A enzyme
Nicotine Amine oxidase [flavin-containing] B enzyme
Nicotine Cytochrome P450 19A1 target
Nicotine Choline O-acetyltransferase target
Methysergide 5-hydroxytryptamine receptor 2A target
Methysergide 5-hydroxytryptamine receptor 1A target
Methysergide 5-hydroxytryptamine receptor 7 target
Methysergide 5-hydroxytryptamine receptor 2C target
Methysergide 5-hydroxytryptamine receptor 2B target
Methysergide 5-hydroxytryptamine receptor 1B target
Methysergide 5-hydroxytryptamine receptor 1F target
Methysergide 5-hydroxytryptamine receptor 1E target
Methysergide Cytochrome P450 3A4 enzyme
Theophylline cGMP-inhibited 3',5'-cyclic phosphodiesterase A target
Theophylline cAMP-specific 3',5'-cyclic phosphodiesterase 4B target
Theophylline Adenosine receptor A2b target
Theophylline cAMP-specific 3',5'-cyclic phosphodiesterase 4A target
Theophylline cGMP-specific 3',5'-cyclic phosphodiesterase target
Theophylline Adenosine receptor A1 target
Theophylline Adenosine receptor A2a target
Theophylline Cytochrome P450 1A2 enzyme
Theophylline Adenosine deaminase enzyme
Theophylline Cytochrome P450 2E1 enzyme
Theophylline Cytochrome P450 3A4 enzyme
Theophylline Solute carrier family 22 member 7 transporter
Theophylline Cytochrome P450 1A1 enzyme
Theophylline Cytochrome P450 1B1 enzyme
Theophylline Cytochrome P450 2D6 enzyme
Theophylline Histone deacetylase 2 target
Theophylline Copine-1 target
Theophylline Minor histocompatibility antigen H13 target
Theophylline Nodal modulator 1 target
Theophylline Poly [ADP-ribose] polymerase 1 target
Theophylline Protein RIC-3 target
Theophylline Tubulin monoglycylase TTLL3 target
Methylergometrine 多巴胺D1受体 target
Methylergometrine Cytochrome P450 3A4 enzyme
Methylergometrine 5-hydroxytryptamine receptor 2B target
Metocurine iodide Neuronal acetylcholine receptor subunit alpha-2 target
Miglustat Ceramide glucosyltransferase target
Methscopolamine bromide Muscarinic acetylcholine receptor M1 target
Methscopolamine bromide Muscarinic acetylcholine receptor M2 target
Methscopolamine bromide Muscarinic acetylcholine receptor M3 target
Miglitol Maltase-glucoamylase, intestinal target
Miglitol Pancreatic alpha-amylase enzyme
Miglitol Lysosomal alpha-glucosidase target
Miglitol Neutral alpha-glucosidase AB target
Miglitol Neutral alpha-glucosidase C target
Levallorphan Mu-type opioid receptor target
Anisotropine methylbromide Muscarinic acetylcholine receptor M1 target
Anisotropine methylbromide Muscarinic acetylcholine receptor M2 target
Anisotropine methylbromide Muscarinic acetylcholine receptor M3 target
Butorphanol Kappa-type opioid receptor target
Butorphanol Mu-type opioid receptor target
Butorphanol Delta-type opioid receptor target
Pentazocine Mu-type opioid receptor target
Pentazocine Kappa-type opioid receptor target
Pentazocine Sigma non-opioid intracellular receptor 1 target
Pentazocine P-glycoprotein 1 transporter
Ergotamine Alpha-1A adrenergic receptor target
Ergotamine 5-hydroxytryptamine receptor 1D target
Ergotamine 5-hydroxytryptamine receptor 1B target
Ergotamine 5-hydroxytryptamine receptor 2A target
Ergotamine Alpha-2A adrenergic receptor target
Ergotamine Dopamine D2 receptor target
Ergotamine Cytochrome P450 3A4 enzyme
Ergotamine Alpha-1B adrenergic receptor target
Ergotamine Alpha-1D adrenergic receptor target
Ergotamine P-glycoprotein 1 transporter
Ergotamine D(1) dopamine receptor target
Ergotamine 5-hydroxytryptamine receptor 1A target
Ergotamine 5-hydroxytryptamine receptor 1F target
Ergotamine 5-hydroxytryptamine receptor 2C target
Ergotamine 5-hydroxytryptamine receptor 2B target
Ergotamine Alpha-2C adrenergic receptor target
Nicergoline Alpha-1A adrenergic receptor target
Nicergoline Cytochrome P450 2D6 enzyme
Naltrexone Mu-type opioid receptor target
Naltrexone Kappa-type opioid receptor target
Naltrexone Delta-type opioid receptor target
Naltrexone UDP-glucuronosyltransferase 1-1 enzyme
Naltrexone Sigma non-opioid intracellular receptor 1 target
Homatropine methylbromide Muscarinic acetylcholine receptor M2 target
Homatropine methylbromide Muscarinic acetylcholine receptor M1 target
Homatropine methylbromide Muscarinic acetylcholine receptor M4 target
Homatropine methylbromide Muscarinic acetylcholine receptor M5 target
Homatropine methylbromide Muscarinic acetylcholine receptor M3 target
Cryptenamine Muscarinic acetylcholine receptor M2 target
Cryptenamine Beta adrenergic receptor target
Enprofylline cAMP-specific 3',5'-cyclic phosphodiesterase 4B target
Enprofylline Adenosine receptor A2b target
Enprofylline cAMP-specific 3',5'-cyclic phosphodiesterase 4A target
Enprofylline Adenosine receptor A1 target
Enprofylline Adenosine receptor A2a target
Enprofylline Adenosine receptor A3 target
Nalbuphine Kappa-type opioid receptor target
Nalbuphine Mu-type opioid receptor target
Nalbuphine Delta-type opioid receptor target
Levorphanol Mu-type opioid receptor target
Levorphanol Delta-type opioid receptor target
Levorphanol Kappa-type opioid receptor target
Buprenorphine Kappa-type opioid receptor target
Buprenorphine Mu-type opioid receptor target
Buprenorphine Cytochrome P450 3A4 enzyme
Buprenorphine Cytochrome P450 2D6 enzyme
Buprenorphine P-glycoprotein 1 transporter
Buprenorphine ATP-binding cassette sub-family G member 2 transporter
Buprenorphine Cytochrome P450 2C9 enzyme
Buprenorphine Cytochrome P450 3A5 enzyme
Buprenorphine Cytochrome P450 2C8 enzyme
Buprenorphine Cytochrome P450 3A7 enzyme
Buprenorphine Delta-type opioid receptor target
Buprenorphine Cytochrome P450 2C18 enzyme
Buprenorphine Cytochrome P450 2C19 enzyme
Buprenorphine Nociceptin receptor target
Physostigmine Acetylcholinesterase target
Physostigmine Neuronal acetylcholine receptor subunit alpha-4 target
Physostigmine Neuronal acetylcholine receptor subunit beta-2 target
Ergoloid mesylate Dopamine receptor target
Ergoloid mesylate Alpha adrenergic receptor target
Ergoloid mesylate Beta adrenergic receptor target
Ergoloid mesylate Serotonin Receptors target
Ergoloid mesylate Cytochrome P450 3A4 enzyme
Deserpidine Synaptic vesicular amine transporter target
Rescinnamine Angiotensin-converting enzyme target
Oxymorphone Mu-type opioid receptor target
Oxymorphone Cytochrome P450 2D6 enzyme
Oxymorphone Delta-type opioid receptor target
Oxymorphone Cytochrome P450 3A4 enzyme
Bromocriptine Dopamine D2 receptor target
Bromocriptine Cytochrome P450 3A4 enzyme
Bromocriptine 5-hydroxytryptamine receptor 1D target
Bromocriptine Alpha-2A adrenergic receptor target
Bromocriptine Dopamine D3 receptor target
Bromocriptine 5-hydroxytryptamine receptor 1A target
Bromocriptine Alpha-2C adrenergic receptor target
Bromocriptine Alpha-2B adrenergic receptor target
Bromocriptine 5-hydroxytryptamine receptor 2B target
Bromocriptine Dopamine D4 receptor target
Bromocriptine 5-hydroxytryptamine receptor 2A target
Bromocriptine 5-hydroxytryptamine receptor 1B target
Bromocriptine 5-hydroxytryptamine receptor 2C target
Bromocriptine Dopamine D5 receptor target
Bromocriptine 多巴胺D1受体 target
Bromocriptine Alpha-1A adrenergic receptor target
Bromocriptine Alpha-1B adrenergic receptor target
Bromocriptine Alpha-1D adrenergic receptor target
Bromocriptine 5-hydroxytryptamine receptor 7 target
Bromocriptine P-glycoprotein 1 transporter
Ergometrine Cytochrome P450 3A4 enzyme
Ergometrine P-glycoprotein 1 transporter
Ergometrine Alpha-1A adrenergic receptor target
Oxtriphylline cGMP-inhibited 3',5'-cyclic phosphodiesterase A target
Oxtriphylline cAMP-specific 3',5'-cyclic phosphodiesterase 4A target
Oxtriphylline Adenosine receptor A2a target
Oxtriphylline Adenosine receptor A1 target
Oxtriphylline Cytochrome P450 1A2 enzyme
Oxtriphylline Solute carrier family 22 member 7 transporter
Oxtriphylline Histone deacetylase 2 target
Metocurine Neuronal acetylcholine receptor subunit alpha-2 target
Metocurine Muscarinic acetylcholine receptor M2 target
Yohimbine Alpha-2A adrenergic receptor target
Yohimbine Alpha-2B adrenergic receptor target
Yohimbine Alpha-2C adrenergic receptor target
Yohimbine 5-hydroxytryptamine receptor 1A target
Yohimbine 5-hydroxytryptamine receptor 1B target
Yohimbine 5-hydroxytryptamine receptor 1D target
Yohimbine Dopamine D2 receptor target
Yohimbine Dopamine D3 receptor target
Yohimbine 5-hydroxytryptamine receptor 2A target
Yohimbine 5-hydroxytryptamine receptor 2C target
Yohimbine Cytochrome P450 2D6 enzyme
Yohimbine Cytochrome P450 3A4 enzyme
Yohimbine ATP-sensitive potassium channel target
Yohimbine 5-hydroxytryptamine receptor 2B target
Theobromine Cytochrome P450 1A2 enzyme
Theobromine Cytochrome P450 2E1 enzyme
Theobromine Adenosine receptor A1 target
Theobromine Adenosine receptor A2a target
Theobromine cAMP-specific 3',5'-cyclic phosphodiesterase 4B target
Almitrine Sodium/potassium-transporting ATPase subunit alpha-1 target
Diamorphine Mu-type opioid receptor target
Diamorphine Kappa-type opioid receptor target
Diamorphine Delta-type opioid receptor target
Diamorphine Liver carboxylesterase 1 target
Diamorphine Thyroxine-binding globulin carrier
Ethylmorphine Cytochrome P450 2D6 enzyme
Ethylmorphine NADPH--cytochrome P450 reductase enzyme
Ethylmorphine Mu-type opioid receptor target
Ethylmorphine Cytochrome P450 2B6 enzyme
Ethylmorphine Cytochrome P450 3A4 enzyme
Fenethylline Cytochrome P450 1A2 enzyme
Etorphine E3 ubiquitin-protein ligase TRIM13 target
Etorphine Pro-opiomelanocortin target
Etorphine Mu-type opioid receptor target
Etorphine Delta-type opioid receptor target
Etorphine Kappa-type opioid receptor target
Etorphine Nociceptin receptor target
Diprenorphine E3 ubiquitin-protein ligase TRIM13 target
Diprenorphine Delta-type opioid receptor target
Diprenorphine Kappa-type opioid receptor target
Diprenorphine Mu-type opioid receptor target
Dihydrocodeine Cytochrome P450 2D6 enzyme
Dihydrocodeine Cytochrome P450 3A4 enzyme
Dihydromorphine E3 ubiquitin-protein ligase TRIM13 target
Dihydromorphine Pro-opiomelanocortin target
Dihydromorphine Mu-type opioid receptor target
Dihydromorphine Delta-type opioid receptor target
Dihydromorphine Kappa-type opioid receptor target
8-azaxanthine Uric acid degradation bifunctional protein target
7-Hydroxystaurosporine 3-phosphoinositide-dependent protein kinase 1 target
Staurosporine Tyrosine-protein kinase Lck target
Staurosporine Serine/threonine-protein kinase pim-1 target
Staurosporine Tyrosine-protein kinase ITK/TSK target
Staurosporine Tyrosine-protein kinase SYK target
Staurosporine MAP kinase-activated protein kinase 2 target
Staurosporine Glycogen synthase kinase-3 beta target
Staurosporine Tyrosine-protein kinase CSK target
Staurosporine Cyclin-dependent kinase 2 target
Staurosporine Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform target
Staurosporine 3-phosphoinositide-dependent protein kinase 1 target
Staurosporine Protein kinase C theta type target
Staurosporine Tyrosine-protein kinase ZAP-70 target
Staurosporine P-glycoprotein 1 transporter
Staurosporine Muscarinic acetylcholine receptor M1 target
Staurosporine Protein kinase C target
Xanthine Purine nucleoside phosphorylase 2 target
Xanthine Xanthine phosphoribosyltransferase target
Xanthine Cytochrome P450 1A2 enzyme
Deacetoxyvinzolidine Calmodulin target
Berberine HTH-type transcriptional regulator QacR target
Berberine Baculoviral IAP repeat-containing protein 5 target
Calystegine B2 Beta-glucosidase A target
Methylecgonine Ig gamma-2 chain C region target
Methylecgonine Ig kappa chain C region target
Lysergic acid diethylamide 5-hydroxytryptamine receptor 1A target
Lysergic acid diethylamide 5-hydroxytryptamine receptor 2B target
Lysergic acid diethylamide 5-hydroxytryptamine receptor 6 target
Lysergic acid diethylamide Cytochrome P450 3A4 enzyme
Lysergic acid diethylamide Cytochrome P450 2D6 enzyme
Voacamine P-glycoprotein 1 target
Voacamine P-glycoprotein 1 transporter
Phenserine Acetylcholinesterase target
Phenserine Cholinesterase target
Phenserine Amyloid beta A4 protein target
Altropane Sodium-dependent dopamine transporter target
Migalastat Alpha-galactosidase A target
Migalastat UDP-glucuronosyltransferase 1-1 enzyme
Vintafolide Folate receptor beta target
Vintafolide Folate receptor gamma target
Vintafolide Folate receptor alpha target
7-ethyl-10-hydroxycamptothecin DNA topoisomerase 1 target
7-ethyl-10-hydroxycamptothecin Cytochrome P450 3A4 enzyme
Cositecan DNA topoisomerase 1 target
Rivanicline Neuronal acetylcholine receptor subunit beta-2 target
Rivanicline Interleukin-8 target
XMT-1001 DNA topoisomerase 1 target
Rubitecan DNA topoisomerase 1 target
Nalmefene Mu-type opioid receptor target
Nalmefene Kappa-type opioid receptor target
Nalmefene Delta-type opioid receptor target
Nalmefene UDP-glucuronosyltransferase 2B7 enzyme
Nalmefene UDP-glucuronosyltransferase 1-3 enzyme
Nalmefene UDP-glucuronosyltransferase 1-8 enzyme
Nalmefene Cytochrome P450 3A4 enzyme
Nalmefene Cytochrome P450 3A5 enzyme
Morphine glucuronide Mu-type opioid receptor target
Morphine glucuronide Delta-type opioid receptor target
Morphine glucuronide Kappa-type opioid receptor target
Naxifylline Adenosine receptor A1 target
Propentofylline cAMP-specific 3',5'-cyclic phosphodiesterase 4A target
Propentofylline Cytochrome P450 1A2 enzyme
Midostaurin Protein kinase C alpha type target
Midostaurin Vascular endothelial growth factor receptor 2 target
Midostaurin Mast/stem cell growth factor receptor Kit target
Midostaurin Platelet-derived growth factor receptor alpha target
Midostaurin Platelet-derived growth factor receptor beta target
Midostaurin Receptor-type tyrosine-protein kinase FLT3 target
Midostaurin Cytochrome P450 3A Subfamily enzyme
Midostaurin Cytochrome P450 1A2 enzyme
Midostaurin Cytochrome P450 2B6 enzyme
Midostaurin Cytochrome P450 2C8 enzyme
Midostaurin Cytochrome P450 2C9 enzyme
Midostaurin Cytochrome P450 2C19 enzyme
Midostaurin Cytochrome P450 2D6 enzyme
Midostaurin Cytochrome P450 2E1 enzyme
Midostaurin Cytochrome P450 3A4 enzyme
Midostaurin Cytochrome P450 3A5 enzyme
Midostaurin Cytochrome P450 3A7 enzyme
Midostaurin Cytochrome P450 3A43 enzyme
Gimatecan Solute carrier organic anion transporter family member 1B1 transporter
Capsaicin Cytochrome P450 3A4 enzyme
Capsaicin Prostaglandin G/H synthase 2 enzyme
Capsaicin Myeloperoxidase enzyme
Capsaicin Cytochrome P450 1A2 enzyme
Capsaicin Cytochrome P450 2E1 enzyme
Capsaicin Amine oxidase [flavin-containing] A enzyme
Capsaicin Dopamine beta-hydroxylase enzyme
Capsaicin Glutamine synthetase enzyme
Capsaicin Cholinesterase enzyme
Capsaicin Transient receptor potential cation channel subfamily V member 1 target
Capsaicin Prohibitin-2 target
Methylnaltrexone Mu-type opioid receptor target
Methylnaltrexone Kappa-type opioid receptor target
Harmine Amine oxidase [flavin-containing] A target
Ioflupane I-123 Sodium-dependent dopamine transporter transporter
Uric acid Solute carrier family 22 member 6 transporter
Uric acid Solute carrier family 22 member 8 transporter
Uric acid Glycogen phosphorylase, liver form target
Uric acid Solute carrier family 2, facilitated glucose transporter member 9 transporter
Aclidinium Muscarinic acetylcholine receptor M1 target
Aclidinium Muscarinic acetylcholine receptor M2 target
Aclidinium Muscarinic acetylcholine receptor M3 target
Aclidinium Muscarinic acetylcholine receptor M4 target
Aclidinium Muscarinic acetylcholine receptor M5 target
Aclidinium Cholinesterase enzyme
Naloxegol Cytochrome P450 3A4 enzyme
Naloxegol Cytochrome P450 2D6 enzyme
Naloxegol Cytochrome P450 2C19 enzyme
Naloxegol Mu-type opioid receptor target
Zucapsaicin Transient receptor potential cation channel subfamily V member 1 target
Zucapsaicin Cytochrome P450 1A2 enzyme
Zucapsaicin Cytochrome P450 2C19 enzyme
Zucapsaicin Cytochrome P450 2C9 enzyme
Zucapsaicin Cytochrome P450 2E1 enzyme
Pholcodine Mu-type opioid receptor target
Pholcodine Kappa-type opioid receptor target
Pholcodine Delta-type opioid receptor target
Doxofylline Phosphodiesterase 2A, cGMP-stimulated target
Doxofylline Adenosine receptor A2a target
Doxofylline Beta-2 adrenergic receptor target
Doxofylline Cytochrome P450 1A2 enzyme
Butylscopolamine Muscarinic acetylcholine receptor M3 target
Butylscopolamine Muscarinic acetylcholine receptor M2 target
Dihydroergocornine Serotonin Receptors target
Dihydroergocornine Beta adrenergic receptor target
Dihydroergocornine Alpha adrenergic receptor target
Dihydroergocornine Cytochrome P450 3A4 enzyme
Epicriptine Dopamine receptor target
Nonivamide Transient receptor potential cation channel subfamily V member 1 target
Thiocolchicoside GABA(A) Receptor target
Thiocolchicoside Glycine receptor subunit alpha-1 target
Thiocolchicoside Tumor necrosis factor ligand superfamily member 11 target
Naldemedine Cytochrome P450 3A Subfamily enzyme
Naldemedine UDP-glucuronosyltransferase 1-3 enzyme
Naldemedine Mu-type opioid receptor target
Naldemedine Delta-type opioid receptor target
Naldemedine Kappa-type opioid receptor target
Naldemedine ATP-binding cassette sub-family B member 5 transporter
Anisodamine Cytochrome P450 2D6 enzyme
Tetrahydropalmatine 多巴胺D1受体 target
Tetrahydropalmatine Dopamine D2 receptor target
Tetrahydropalmatine Cytochrome P450 3A4 enzyme
Vinpocetine Cytochrome P450 3A4 enzyme
9-aminocamptothecin Cytochrome P450 3A4 enzyme
Tonapofylline Adenosine receptor A1 target
Rolofylline Adenosine receptor A1 target
Ambroxol acefyllinate Cytochrome P450 3A Subfamily enzyme
Bamifylline Cytochrome P450 1A2 enzyme
Dihydroergocristine Serotonin Receptors target
Dihydroergocristine Beta adrenergic receptor target
Dihydroergocristine Alpha adrenergic receptor target
Dihydroergocristine Dopamine receptor target
Dihydroergocristine Bile salt export pump transporter
Dihydroergocristine Cytochrome P450 3A4 enzyme
Dihydroergocryptine Cytochrome P450 3A4 enzyme
Terguride Cytochrome P450 3A4 enzyme
Proxyphylline Cytochrome P450 1A2 enzyme
Metergoline Sodium channel protein type 2 subunit alpha target
Acefylline Cytochrome P450 1A2 enzyme
Etamiphylline Cytochrome P450 1A2 enzyme
Pentifylline Cytochrome P450 1A2 enzyme
Bufylline Cytochrome P450 1A2 enzyme
Harmaline Histamine N-methyltransferase target
Bromotheophylline Cytochrome P450 1A2 enzyme
Furafylline Cytochrome P450 1A2 enzyme
8-chlorotheophylline Adenosine receptor A2a target
8-chlorotheophylline Cytochrome P450 1A2 enzyme
Loxicodegol Mu-type opioid receptor target
Loxicodegol Delta-type opioid receptor target
Loxicodegol Kappa-type opioid receptor target
Loxicodegol P-glycoprotein 1 transporter
Gibberellic acid Arylacetamide deacetylase-like 2 target
Gibberellin A4 Arylacetamide deacetylase-like 2 target
Cytisine Neuronal acetylcholine receptor subunit alpha-4 target
Cytisine Neuronal acetylcholine receptor subunit alpha-7 target
Cytisine Neuronal acetylcholine receptor subunit alpha-3 target
Cytisine Neuronal acetylcholine receptor subunit alpha-6 target
Cytisine Neuronal acetylcholine receptor subunit beta-2 target